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225 results for Talin+-+metabolism

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Mechanical stress determines the configuration of TGFβ activation in articular cartilage
Author / Creator:Zhen, Gehua ; Guo, Qiaoyue ; Li, Yusheng ; Wu, Chuanlong ; Zhu, Shouan ; Wang, Ruomei ; Guo, X. Edward ; Kim, Byoung Choul ; Huang, Jessie ; Hu, Yizhong ; Dan, Yang ; Wan, Mei ; Ha, Taekjip ; An, Steven ; Cao, Xu
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-03, Vol.12 (1), p.1706-16, Article 1706
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Integrin activation by talin, kindlin and mechanical forces
Author / Creator:Sun, Zhiqi ; Costell, Mercedes ; Fässler, Reinhard
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2019-01, Vol.21 (1), p.25-31
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Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity
Author / Creator:Elosegui-Artola, Alberto ; Oria, Roger ; Chen, Yunfeng ; Kosmalska, Anita ; Pérez-González, Carlos ; Castro, Natalia ; Zhu, Cheng ; Trepat, Xavier ; Roca-Cusachs, Pere
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2016-05, Vol.18 (5), p.540-548
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Mechanism of integrin activation by talin and its cooperation with kindlin
Author / Creator:Lu, Fan ; Zhu, Liang ; Bromberger, Thomas ; Yang, Jun ; Yang, Qiannan ; Liu, Jianmin ; Plow, Edward F. ; Moser, Markus ; Qin, Jun
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-04, Vol.13 (1), p.2362-19, Article 2362
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The mechanical response of talin
Author / Creator:Yao, Mingxi ; Goult, Benjamin T. ; Klapholz, Benjamin ; Hu, Xian ; Toseland, Christopher P. ; Guo, Yingjian ; Cong, Peiwen ; Sheetz, Michael P. ; Yan, Jie
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-07, Vol.7 (1), p.11966-11966, Article 11966
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Mechanical activation of vinculin binding to talin locks talin in an unfolded conformation
Author / Creator:Yao, Mingxi ; Goult, Benjamin T. ; Chen, Hu ; Cong, Peiwen ; Sheetz, Michael P. ; Yan, Jie
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2014-04, Vol.4 (1), p.4610-4610, Article 4610
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The C-terminal actin-binding domain of talin forms an asymmetric catch bond with F-actin
Author / Creator:Owen, Leanna M. ; Bax, Nicolas A. ; Weis, William I. ; Dunn, Alexander R.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2022-03, Vol.119 (10), p.1-7
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Integrins β1 and β3 exhibit distinct dynamic nanoscale organizations inside focal adhesions
Author / Creator:Rossier, Olivier ; Octeau, Vivien ; Sibarita, Jean-Baptiste ; Leduc, Cécile ; Tessier, Béatrice ; Nair, Deepak ; Gatterdam, Volker ; Destaing, Olivier ; Albigès-Rizo, Corinne ; Tampé, Robert ; Cognet, Laurent ; Choquet, Daniel ; Lounis, Brahim ; Giannone, Grégory
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2012-10, Vol.14 (10), p.1057-1067
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Stretching Single Talin Rod Molecules Activates Vinculin Binding
Author / Creator:Rio, Armando del ; Perez-Jimenez, Raul ; Liu, Ruchuan ; Roca-Cusachs, Pere ; Fernandez, Julio M. ; Sheetz, Michael P.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2009-01, Vol.323 (5914), p.638-641
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Integrin-dependent force transmission to the extracellular matrix by α-actinin triggers adhesion maturation
Author / Creator:Roca-Cusachs, Pere ; del Rio, Armando ; Puklin-Faucher, Eileen ; Gauthier, Nils C. ; Biais, Nicolas ; Sheetz, Michael P.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-04, Vol.110 (15), p.E1361-E1370
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The final steps of integrin activation: the end game
Author / Creator:Shattil, Sanford J. ; Kim, Chungho ; Ginsberg, Mark H.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Molecular cell biology, 2010-04, Vol.11 (4), p.288-300
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Extracellular rigidity sensing by talin isoform-specific mechanical linkages
Author / Creator:Austen, Katharina ; Ringer, Pia ; Mehlich, Alexander ; Chrostek-Grashoff, Anna ; Kluger, Carleen ; Klingner, Christoph ; Sabass, Benedikt ; Zent, Roy ; Rief, Matthias ; Grashoff, Carsten
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2015-12, Vol.17 (12), p.1597-1606
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Molecular mechanism of vinculin activation and nanoscale spatial organization in focal adhesions
Author / Creator:Case, Lindsay B. ; Baird, Michelle A. ; Shtengel, Gleb ; Campbell, Sharon L. ; Hess, Harald F. ; Davidson, Michael W. ; Waterman, Clare M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2015-07, Vol.17 (7), p.880-892
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Fibronectin-bound α5β1 integrins sense load and signal to reinforce adhesion in less than a second
Author / Creator:Strohmeyer, Nico ; Bharadwaj, Mitasha ; Costell, Mercedes ; Fässler, Reinhard ; Müller, Daniel J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature materials, 2017-12, Vol.16 (12), p.1262-1270
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Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin
Author / Creator:Theodosiou, Marina ; Widmaier, Moritz ; Böttcher, Ralph T ; Rognoni, Emanuel ; Veelders, Maik ; Bharadwaj, Mitasha ; Lambacher, Armin ; Austen, Katharina ; Müller, Daniel J ; Zent, Roy ; Fässler, Reinhard
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2016-01, Vol.5, p.e10130-e10130
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The force loading rate drives cell mechanosensing through both reinforcement and cytoskeletal softening
Author / Creator:Andreu, Ion ; Falcones, Bryan ; Hurst, Sebastian ; Chahare, Nimesh ; Quiroga, Xarxa ; Le Roux, Anabel-Lise ; Kechagia, Zanetta ; Beedle, Amy E. M. ; Elosegui-Artola, Alberto ; Trepat, Xavier ; Farré, Ramon ; Betz, Timo ; Almendros, Isaac ; Roca-Cusachs, Pere
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-07, Vol.12 (1), p.4229-4229, Article 4229
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Vinculin controls talin engagement with the actomyosin machinery
Author / Creator:Atherton, Paul ; Stutchbury, Ben ; Wang, De-Yao ; Jethwa, Devina ; Tsang, Ricky ; Meiler-Rodriguez, Eugenia ; Wang, Pengbo ; Bate, Neil ; Zent, Roy ; Barsukov, Igor L. ; Goult, Benjamin T. ; Critchley, David R. ; Ballestrem, Christoph
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-12, Vol.6 (1), p.10038-10038, Article 10038
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Kank2 activates talin, reduces force transduction across integrins and induces central adhesion formation
Author / Creator:Sun, Zhiqi ; Tseng, Hui-Yuan ; Tan, Steven ; Senger, Fabrice ; Kurzawa, Laetitia ; Dedden, Dirk ; Mizuno, Naoko ; Wasik, Anita A. ; Thery, Manuel ; Dunn, Alexander R. ; Fässler, Reinhard
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2016-09, Vol.18 (9), p.941-953
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Allosteric activation of vinculin by talin
Author / Creator:Franz, Florian ; Tapia-Rojo, Rafael ; Winograd-Katz, Sabina ; Boujemaa-Paterski, Rajaa ; Li, Wenhong ; Unger, Tamar ; Albeck, Shira ; Aponte-Santamaria, Camilo ; Garcia-Manyes, Sergi ; Medalia, Ohad ; Geiger, Benjamin ; Gräter, Frauke
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-07, Vol.14 (1), p.4311-4311, Article 4311
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Reticular adhesions are a distinct class of cell-matrix adhesions that mediate attachment during mitosis
Author / Creator:Lock, John G. ; Jones, Matthew C. ; Askari, Janet A. ; Gong, Xiaowei ; Oddone, Anna ; Olofsson, Helene ; Göransson, Sara ; Lakadamyali, Melike ; Humphries, Martin J. ; Strömblad, Staffan
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2018-11, Vol.20 (11), p.1290-1302
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Showing 1 to 20 of 225 results

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Mechanical stress determines the configuration of TGFβ activation in articular cartilage

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Integrin activation by talin, kindlin and mechanical forces

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Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity

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Mechanism of integrin activation by talin and its cooperation with kindlin

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The mechanical response of talin

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Mechanical activation of vinculin binding to talin locks talin in an unfolded conformation

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The C-terminal actin-binding domain of talin forms an asymmetric catch bond with F-actin

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Integrins β1 and β3 exhibit distinct dynamic nanoscale organizations inside focal adhesions

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Stretching Single Talin Rod Molecules Activates Vinculin Binding

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Integrin-dependent force transmission to the extracellular matrix by α-actinin triggers adhesion maturation

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The final steps of integrin activation: the end game

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Extracellular rigidity sensing by talin isoform-specific mechanical linkages

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Molecular mechanism of vinculin activation and nanoscale spatial organization in focal adhesions

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Fibronectin-bound α5β1 integrins sense load and signal to reinforce adhesion in less than a second

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Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin

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The force loading rate drives cell mechanosensing through both reinforcement and cytoskeletal softening

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Vinculin controls talin engagement with the actomyosin machinery

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Kank2 activates talin, reduces force transduction across integrins and induces central adhesion formation

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Allosteric activation of vinculin by talin

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Reticular adhesions are a distinct class of cell-matrix adhesions that mediate attachment during mitosis

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