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3,351 results for NLR+Family,+Pyrin+Domain-Containing+3+Protein

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ArticlesPeer ReviewedFull Text
Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice
Author / Creator:Monnerat, Gustavo ; Alarcón, Micaela L. ; Vasconcellos, Luiz R. ; Hochman-Mendez, Camila ; Brasil, Guilherme ; Bassani, Rosana A. ; Casis, Oscar ; Malan, Daniela ; Travassos, Leonardo H. ; Sepúlveda, Marisa ; Burgos, Juan Ignacio ; Vila-Petroff, Martin ; Dutra, Fabiano F. ; Bozza, Marcelo T. ; Paiva, Claudia N. ; Carvalho, Adriana Bastos ; Bonomo, Adriana ; Fleischmann, Bernd K. ; de Carvalho, Antonio Carlos Campos ; Medei, Emiliano
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-11, Vol.7 (1), p.13344-13344, Article 13344
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Mitochondrial electron transport chain is necessary for NLRP3 inflammasome activation
Author / Creator:Billingham, Leah K. ; Stoolman, Joshua S. ; Vasan, Karthik ; Rodriguez, Arianne E. ; Poor, Taylor A. ; Szibor, Marten ; Jacobs, Howard T. ; Reczek, Colleen R. ; Rashidi, Aida ; Zhang, Peng ; Miska, Jason ; Chandel, Navdeep S.
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2022-05, Vol.23 (5), p.692-704
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MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition
Author / Creator:Coll, Rebecca C. ; Hill, James R. ; Day, Christopher J. ; Zamoshnikova, Alina ; Boucher, Dave ; Massey, Nicholas L. ; Chitty, Jessica L. ; Fraser, James A. ; Jennings, Michael P. ; Robertson, Avril A. B. ; Schroder, Kate
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2019-06, Vol.15 (6), p.556-559
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NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathway
Author / Creator:Hafner-Bratkovič, Iva ; Sušjan, Petra ; Lainšček, Duško ; Tapia-Abellán, Ana ; Cerović, Kosta ; Kadunc, Lucija ; Angosto-Bazarra, Diego ; Pelegrin, Pablo ; Jerala, Roman
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-12, Vol.9 (1), p.5182-18, Article 5182
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NLRP3 mutation and cochlear autoinflammation cause syndromic and nonsyndromic hearing loss DFNA34 responsive to anakinra therapy
Author / Creator:Nakanishi, Hiroshi ; Kawashima, Yoshiyuki ; Kurima, Kiyoto ; Chae, Jae Jin ; Ross, Astin M. ; Pinto-Patarroyo, Gineth ; Patel, Seema K. ; Muskett, Julie A. ; Ratay, Jessica S. ; Chattaraj, Parna ; Park, Yong Hwan ; Grevich, Sriharsha ; Brewer, Carmen C. ; Hoa, Michael ; Kim, H. Jeffrey ; Butman, John A. ; Broderick, Lori ; Hoffman, Hal M. ; Aksentijevich, Ivona ; Kastner, Daniel L. ; Goldbach-Mansky, Raphaela ; Griffith, Andrew J.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-09, Vol.114 (37), p.E7766-E7775
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NLRP3 inflammasome activation drives tau pathology
Author / Creator:Ising, Christina ; Venegas, Carmen ; Zhang, Shuangshuang ; Scheiblich, Hannah ; Schmidt, Susanne V. ; Vieira-Saecker, Ana ; Schwartz, Stephanie ; Albasset, Shadi ; McManus, Róisín M. ; Tejera, Dario ; Griep, Angelika ; Santarelli, Francesco ; Brosseron, Frederic ; Opitz, Sabine ; Stunden, James ; Merten, Maximilian ; Kayed, Rakez ; Golenbock, Douglas T. ; Blum, David ; Latz, Eicke ; Buée, Luc ; Heneka, Michael T.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-11, Vol.575 (7784), p.669-673
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NLRP3 regulates alveolar bone loss in ligature‐induced periodontitis by promoting osteoclastic differentiation
Author / Creator:Chen, Yuyi ; Yang, Qiudong ; Lv, Chunhua ; Chen, Yue ; Zhao, Wenhua ; Li, Wenlei ; Chen, Hongyu ; Wang, Hua ; Sun, Wen ; Yuan, Hua
Publisher:England: John Wiley & Sons, Inc
Journal title:Cell proliferation, 2021-02, Vol.54 (2), p.e12973-n/a
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Target of MCC950 in Inhibition of NLRP3 Inflammasome Activation: a Literature Review
Author / Creator:Wu, Danbin ; Chen, Yefei ; Sun, Yingxin ; Gao, Qing ; Li, Huhu ; Yang, Zhengfei ; Wang, Yangxue ; Jiang, Xijuan ; Yu, Bin
Publisher:New York: Springer US
Journal title:Inflammation, 2020-02, Vol.43 (1), p.17-23
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RRx-001 ameliorates inflammatory diseases by acting as a potent covalent NLRP3 inhibitor
Author / Creator:Chen, Yun ; He, Hongbin ; Lin, Bolong ; Chen, Yun ; Deng, Xianming ; Jiang, Wei ; Zhou, Rongbin
Publisher:London: Nature Publishing Group UK
Journal title:Cellular & molecular immunology, 2021-06, Vol.18 (6), p.1425-1436
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NLRP3 inflammasome: a promising target in ischemic stroke
Author / Creator:Gao, Li ; Dong, Qing ; Song, Zhenghong ; Shen, Fei ; Shi, Jianquan ; Li, Yansheng
Publisher:Cham: Springer International Publishing
Journal title:Inflammation research, 2017-01, Vol.66 (1), p.17-24
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SGLT-2 Inhibition with Dapagliflozin Reduces the Activation of the Nlrp3/ASC Inflammasome and Attenuates the Development of Diabetic Cardiomyopathy in Mice with Type 2 Diabetes. Further Augmentation o...
Author / Creator:Ye, Yumei ; Bajaj, Mandeep ; Yang, Hsiu-Chiung ; Perez-Polo, Jose R. ; Birnbaum, Yochai
Publisher:New York: Springer US
Journal title:Cardiovascular drugs and therapy, 2017-04, Vol.31 (2), p.119-132
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Modulation of the NLRP3 inflammasome by Sars-CoV-2 Envelope protein
Author / Creator:Yalcinkaya, Mustafa ; Liu, Wenli ; Islam, Mohammad N. ; Kotini, Andriana G. ; Gusarova, Galina A. ; Fidler, Trevor P. ; Papapetrou, Eirini P. ; Bhattacharya, Jahar ; Wang, Nan ; Tall, Alan R.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-12, Vol.11 (1), p.24432-24432, Article 24432
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SARS-CoV-2 N protein promotes NLRP3 inflammasome activation to induce hyperinflammation
Author / Creator:Pan, Pan ; Shen, Miaomiao ; Yu, Zhenyang ; Ge, Weiwei ; Chen, Keli ; Tian, Mingfu ; Xiao, Feng ; Wang, Zhenwei ; Wang, Jun ; Jia, Yaling ; Wang, Wenbiao ; Wan, Pin ; Zhang, Jing ; Chen, Weijie ; Lei, Zhiwei ; Chen, Xin ; Luo, Zhen ; Zhang, Qiwei ; Xu, Meng ; Li, Geng ; Li, Yongkui ; Wu, Jianguo
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-08, Vol.12 (1), p.4664-4664, Article 4664
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An update on the regulatory mechanisms of NLRP3 inflammasome activation
Author / Creator:Paik, Seungwha ; Kim, Jin Kyung ; Silwal, Prashanta ; Sasakawa, Chihiro ; Jo, Eun-Kyeong
Publisher:London: Nature Publishing Group UK
Journal title:Cellular & molecular immunology, 2021-05, Vol.18 (5), p.1141-1160
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MCC950 closes the active conformation of NLRP3 to an inactive state
Author / Creator:Tapia-Abellán, Ana ; Angosto-Bazarra, Diego ; Martínez-Banaclocha, Helios ; de Torre-Minguela, Carlos ; Cerón-Carrasco, Jose P. ; Pérez-Sánchez, Horacio ; Arostegui, Juan I. ; Pelegrin, Pablo
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2019-06, Vol.15 (6), p.560-564
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Cryo-EM structures of the active NLRP3 inflammasome disc
Author / Creator:Xiao, Le ; Magupalli, Venkat Giri ; Wu, Hao
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2023-01, Vol.613 (7944), p.595-600
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Pro-inflammatory role of NLRP3 inflammasome in experimental sterile corneal inflammation
Author / Creator:Shimizu, Hiroaki ; Sakimoto, Tohru ; Yamagami, Satoru
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-07, Vol.9 (1), p.9596-11, Article 9596
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Gypenosides improve diabetic cardiomyopathy by inhibiting ROS‐mediated NLRP3 inflammasome activation
Author / Creator:Zhang, Hailong ; Chen, Xi ; Zong, Beibei ; Yuan, Hongmin ; Wang, Zhizeng ; Wei, Yinxiang ; Wang, Xuance ; Liu, Guangchao ; Zhang, Jun ; Li, Shulian ; Cheng, Guanchang ; Wang, Yaohui ; Ma, Yuanfang
Publisher:England: John Wiley and Sons Inc
Journal title:Journal of cellular and molecular medicine, 2018-09, Vol.22 (9), p.4437-4448
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Tranilast directly targets NLRP3 to treat inflammasome‐driven diseases
Author / Creator:Huang, Yi ; Jiang, Hua ; Chen, Yun ; Wang, Xiaqiong ; Yang, Yanqing ; Tao, Jinhui ; Deng, Xianming ; Liang, Gaolin ; Zhang, Huafeng ; Jiang, Wei ; Zhou, Rongbin
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2018-04, Vol.10 (4), p.1-n/a
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The Role of NLRP3 Inflammasome in the Pathogenesis of Traumatic Brain Injury
Author / Creator:Irrera, Natasha ; Russo, Massimo ; Pallio, Giovanni ; Bitto, Alessandra ; Mannino, Federica ; Minutoli, Letteria ; Altavilla, Domenica ; Squadrito, Francesco
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-08, Vol.21 (17), p.6204
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Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice

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Mitochondrial electron transport chain is necessary for NLRP3 inflammasome activation

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MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition

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NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathway

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NLRP3 mutation and cochlear autoinflammation cause syndromic and nonsyndromic hearing loss DFNA34 responsive to anakinra therapy

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NLRP3 inflammasome activation drives tau pathology

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NLRP3 regulates alveolar bone loss in ligature‐induced periodontitis by promoting osteoclastic differentiation

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Target of MCC950 in Inhibition of NLRP3 Inflammasome Activation: a Literature Review

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RRx-001 ameliorates inflammatory diseases by acting as a potent covalent NLRP3 inhibitor

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NLRP3 inflammasome: a promising target in ischemic stroke

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SGLT-2 Inhibition with Dapagliflozin Reduces the Activation of the Nlrp3/ASC Inflammasome and Attenuates the Development of Diabetic Cardiomyopathy in Mice with Type 2 Diabetes. Further Augmentation o...

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Modulation of the NLRP3 inflammasome by Sars-CoV-2 Envelope protein

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SARS-CoV-2 N protein promotes NLRP3 inflammasome activation to induce hyperinflammation

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An update on the regulatory mechanisms of NLRP3 inflammasome activation

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MCC950 closes the active conformation of NLRP3 to an inactive state

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Cryo-EM structures of the active NLRP3 inflammasome disc

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Pro-inflammatory role of NLRP3 inflammasome in experimental sterile corneal inflammation

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Gypenosides improve diabetic cardiomyopathy by inhibiting ROS‐mediated NLRP3 inflammasome activation

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Tranilast directly targets NLRP3 to treat inflammasome‐driven diseases

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The Role of NLRP3 Inflammasome in the Pathogenesis of Traumatic Brain Injury

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