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Select record 21
ArticlesPeer ReviewedFull Text
LC3 lipidation is essential for TFEB activation during the lysosomal damage response to kidney injury
Author / Creator:Nakamura, Shuhei ; Shigeyama, Saki ; Minami, Satoshi ; Shima, Takayuki ; Akayama, Shiori ; Matsuda, Tomoki ; Esposito, Alessandra ; Napolitano, Gennaro ; Kuma, Akiko ; Namba-Hamano, Tomoko ; Nakamura, Jun ; Yamamoto, Kenichi ; Sasai, Miwa ; Tokumura, Ayaka ; Miyamoto, Mika ; Oe, Yukako ; Fujita, Toshiharu ; Terawaki, Seigo ; Takahashi, Atsushi ; Hamasaki, Maho ; Yamamoto, Masahiro ; Okada, Yukinori ; Komatsu, Masaaki ; Nagai, Takeharu ; Takabatake, Yoshitsugu ; Xu, Haoxing ; Isaka, Yoshitaka ; Ballabio, Andrea ; Yoshimori, Tamotsu
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2020-10, Vol.22 (10), p.1252-1263
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mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases
Author / Creator:Palmieri, Michela ; Pal, Rituraj ; Nelvagal, Hemanth R. ; Lotfi, Parisa ; Stinnett, Gary R. ; Seymour, Michelle L. ; Chaudhury, Arindam ; Bajaj, Lakshya ; Bondar, Vitaliy V. ; Bremner, Laura ; Saleem, Usama ; Tse, Dennis Y. ; Sanagasetti, Deepthi ; Wu, Samuel M. ; Neilson, Joel R. ; Pereira, Fred A. ; Pautler, Robia G. ; Rodney, George G. ; Cooper, Jonathan D. ; Sardiello, Marco
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-02, Vol.8 (1), p.14338-14338, Article 14338
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Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan
Author / Creator:Wang, Chensu ; Niederstrasser, Hanspeter ; Douglas, Peter M. ; Lin, Rueyling ; Jaramillo, Juan ; Li, Yang ; Oswald, Nathaniel W. ; Zhou, Anwu ; McMillan, Elizabeth A. ; Mendiratta, Saurabh ; Wang, Zhaohui ; Zhao, Tian ; Lin, Zhiqaing ; Luo, Min ; Huang, Gang ; Brekken, Rolf A. ; Posner, Bruce A. ; MacMillan, John B. ; Gao, Jinming ; White, Michael A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-12, Vol.8 (1), p.2270-2270, Article 2270
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Macrophage SR-BI modulates autophagy via VPS34 complex and PPARα transcription of Tfeb in atherosclerosis
Author / Creator:Tao, Huan ; Yancey, Patricia G ; Blakemore, John L ; Zhang, Youmin ; Ding, Lei ; Jerome, W Gray ; Brown, Jonathan D ; Vickers, Kasey C ; Linton, MacRae F
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2021-04, Vol.131 (7)
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TFEB–vacuolar ATPase signaling regulates lysosomal function and microglial activation in tauopathy
Author / Creator:Wang, Baiping ; Martini-Stoica, Heidi ; Qi, Chuangye ; Lu, Tzu-Chiao ; Wang, Shuo ; Xiong, Wen ; Qi, Yanyan ; Xu, Yin ; Sardiello, Marco ; Li, Hongjie ; Zheng, Hui
Publisher:New York: Nature Publishing Group US
Journal title:Nature neuroscience, 2024-01, Vol.27 (1), p.48-62
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TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop
Author / Creator:Settembre, Carmine ; De Cegli, Rossella ; Mansueto, Gelsomina ; Saha, Pradip K. ; Vetrini, Francesco ; Visvikis, Orane ; Huynh, Tuong ; Carissimo, Annamaria ; Palmer, Donna ; Jürgen Klisch, Tiemo ; Wollenberg, Amanda C. ; Di Bernardo, Diego ; Chan, Lawrence ; Irazoqui, Javier E. ; Ballabio, Andrea
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2013-06, Vol.15 (6), p.647-658
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Genetic and chemical activation of TFEB mediates clearance of aggregated α-synuclein
Author / Creator:Kilpatrick, Kiri ; Zeng, Yimeng ; Hancock, Tommy ; Segatori, Laura
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-03, Vol.10 (3), p.e0120819-e0120819
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TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity
Author / Creator:Decressac, Mickael ; Mattsson, Bengt ; Weikop, Pia ; Lundblad, Martin ; Jakobsson, Johan ; Björklund, Anders
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-05, Vol.110 (19), p.7541-7541
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Nuclear miR-30b-5p suppresses TFEB-mediated lysosomal biogenesis and autophagy
Author / Creator:Guo, Huijie ; Pu, Mei ; Tai, Yusi ; Chen, Yuxiang ; Lu, Henglei ; Qiao, Junwen ; Wang, Guanghui ; Chen, Jing ; Qi, Xinming ; Huang, Ruimin ; Tao, Zhouteng ; Ren, Jin
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2021-01, Vol.28 (1), p.320-336
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TFEB rearranged renal cell carcinoma. A clinicopathologic and molecular study of 13 cases. Tumors harboring MALAT1-TFEB, ACTB-TFEB, and the novel NEAT1-TFEB translocations constantly express PDL1
Author / Creator:Caliò, Anna ; Harada, Shuko ; Brunelli, Matteo ; Pedron, Serena ; Segala, Diego ; Portillo, Sofia Canete ; Magi-Galluzzi, Cristina ; Netto, George J. ; Mackinnon, Alexander C. ; Martignoni, Guido
Publisher:New York: Elsevier Inc
Journal title:Modern pathology, 2021-04, Vol.34 (4), p.842-850
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TFEB regulates lysosomal exocytosis of tau and its loss of function exacerbates tau pathology and spreading
Author / Creator:Xu, Yin ; Du, Shuqi ; Marsh, Jacob A. ; Horie, Kanta ; Sato, Chihiro ; Ballabio, Andrea ; Karch, Celeste M. ; Holtzman, David M. ; Zheng, Hui
Publisher:London: Nature Publishing Group UK
Journal title:Molecular psychiatry, 2021-10, Vol.26 (10), p.5925-5939
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Huayu Qutan Recipe promotes lipophagy and cholesterol efflux through the mTORC1/TFEB/ABCA1‐SCARB1 signal axis
Author / Creator:Li, Yue ; Pan, Jiaxiang ; Yu, J. J. Jiajia ; Wu, Xize ; Yang, Guanlin ; Pan, Xue ; Sui, Guoyuan ; Wang, Mingyang ; Cheng, Meijia ; Zhu, Shu ; Tai, He ; Xiao, Honghe ; Xu, Lili ; Wu, Jin ; Yang, Yongju ; Tang, Jing ; Gong, Lihong ; Jia, Lianqun ; Min, Dongyu
Publisher:England: John Wiley & Sons, Inc
Journal title:Journal of cellular and molecular medicine, 2024-04, Vol.28 (8), p.e18257-n/a
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Pharmacological enhancement of TFEB-mediated autophagy alleviated neuronal death in oxidative stress-induced Parkinson’s disease models
Author / Creator:Zhuang, Xu-Xu ; Wang, Sheng-Fang ; Tan, Yuan ; Song, Ju-Xian ; Zhu, Zhou ; Wang, Zi-Ying ; Wu, Ming-Yue ; Cai, Cui-Zan ; Huang, Zhi-Jian ; Tan, Jie-Qiong ; Su, Huan-Xing ; Li, Min ; Lu, Jia-Hong
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2020-02, Vol.11 (2), p.128, Article 128
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A splicing variant of TFEB negatively regulates the TFEB-autophagy pathway
Author / Creator:Park, Jee-Yun ; Sohn, Hee-Young ; Koh, Young Ho ; Jo, Chulman
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-10, Vol.11 (1), p.21119-21119, Article 21119
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3,4‐Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB
Author / Creator:Chen, Guo ; Xie, Wei ; Nah, Jihoon ; Sauvat, Allan ; Liu, Peng ; Pietrocola, Federico ; Sica, Valentina ; Carmona‐Gutierrez, Didac ; Zimmermann, Andreas ; Pendl, Tobias ; Tadic, Jelena ; Bergmann, Martina ; Hofer, Sebastian J ; Domuz, Lana ; Lachkar, Sylvie ; Markaki, Maria ; Tavernarakis, Nektarios ; Sadoshima, Junichi ; Madeo, Frank ; Kepp, Oliver ; Kroemer, Guido
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2019-11, Vol.11 (11), p.e10469-n/a
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Past, present, and future perspectives of transcription factor EB (TFEB): mechanisms of regulation and association with disease
Author / Creator:Tan, Anderson ; Prasad, Renuka ; Lee, Chaerin ; Jho, Eek-hoon
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2022-08, Vol.29 (8), p.1433-1449
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TFEB regulates murine liver cell fate during development and regeneration
Author / Creator:Pastore, Nunzia ; Huynh, Tuong ; Herz, Niculin J. ; Calcagni’, Alessia ; Klisch, Tiemo J. ; Brunetti, Lorenzo ; Kim, Kangho Ho ; De Giorgi, Marco ; Hurley, Ayrea ; Carissimo, Annamaria ; Mutarelli, Margherita ; Aleksieva, Niya ; D’Orsi, Luca ; Lagor, William R. ; Moore, David D. ; Settembre, Carmine ; Finegold, Milton J. ; Forbes, Stuart J. ; Ballabio, Andrea
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-05, Vol.11 (1), p.2461-2461, Article 2461
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MEK1/2 inhibition rescues neurodegeneration by TFEB-mediated activation of autophagic lysosomal function in a model of Alzheimer’s Disease
Author / Creator:Chun, Yoon Sun ; Kim, Mi-Yeon ; Lee, Sun-Young ; Kim, Mi Jeong ; Hong, Tae-Joon ; Jeon, Jae Kyong ; Ganbat, Dulguun ; Kim, Hyoung Tae ; Kim, Sang Seong ; Kam, Tae-In ; Han, Sungho
Publisher:London: Nature Publishing Group UK
Journal title:Molecular psychiatry, 2022-11, Vol.27 (11), p.4770-4780
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TFEB Biology and Agonists at a Glance
Author / Creator:Chen, Mingyue ; Dai, Yashuang ; Liu, Siyu ; Fan, Yuxin ; Ding, Zongxian ; Li, Dan
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2021-02, Vol.10 (2), p.333
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DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity
Author / Creator:Lin, Xin-Xuan ; Sen, Ilke ; Janssens, Georges E. ; Zhou, Xin ; Fonslow, Bryan R. ; Edgar, Daniel ; Stroustrup, Nicholas ; Swoboda, Peter ; Yates, John R. ; Ruvkun, Gary ; Riedel, Christian G.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-10, Vol.9 (1), p.4400-15, Article 4400
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LC3 lipidation is essential for TFEB activation during the lysosomal damage response to kidney injury

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mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases

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Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan

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Macrophage SR-BI modulates autophagy via VPS34 complex and PPARα transcription of Tfeb in atherosclerosis

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TFEB–vacuolar ATPase signaling regulates lysosomal function and microglial activation in tauopathy

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TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop

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Genetic and chemical activation of TFEB mediates clearance of aggregated α-synuclein

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TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity

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Nuclear miR-30b-5p suppresses TFEB-mediated lysosomal biogenesis and autophagy

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TFEB rearranged renal cell carcinoma. A clinicopathologic and molecular study of 13 cases. Tumors harboring MALAT1-TFEB, ACTB-TFEB, and the novel NEAT1-TFEB translocations constantly express PDL1

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TFEB regulates lysosomal exocytosis of tau and its loss of function exacerbates tau pathology and spreading

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Huayu Qutan Recipe promotes lipophagy and cholesterol efflux through the mTORC1/TFEB/ABCA1‐SCARB1 signal axis

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Pharmacological enhancement of TFEB-mediated autophagy alleviated neuronal death in oxidative stress-induced Parkinson’s disease models

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A splicing variant of TFEB negatively regulates the TFEB-autophagy pathway

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3,4‐Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB

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Past, present, and future perspectives of transcription factor EB (TFEB): mechanisms of regulation and association with disease

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TFEB regulates murine liver cell fate during development and regeneration

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MEK1/2 inhibition rescues neurodegeneration by TFEB-mediated activation of autophagic lysosomal function in a model of Alzheimer’s Disease

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TFEB Biology and Agonists at a Glance

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DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity

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