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82 results for Antibodies,+Blocking+-+therapeutic+use

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ArticlesPeer ReviewedFull Text
PD-1-cis IL-2R agonism yields better effectors from stem-like CD8+ T cells
Author / Creator:Codarri Deak, Laura ; Nicolini, Valeria ; Hashimoto, Masao ; Karagianni, Maria ; Schwalie, Petra C. ; Lauener, Laura ; Varypataki, Eleni Maria ; Richard, Marine ; Bommer, Esther ; Sam, Johannes ; Joller, Stefanie ; Perro, Mario ; Cremasco, Floriana ; Kunz, Leo ; Yanguez, Emilio ; Hüsser, Tamara ; Schlenker, Ramona ; Mariani, Marisa ; Tosevski, Vinko ; Herter, Sylvia ; Bacac, Marina ; Waldhauer, Inja ; Colombetti, Sara ; Gueripel, Xavier ; Wullschleger, Stephan ; Tichet, Melanie ; Hanahan, Douglas ; Kissick, Haydn T. ; Leclair, Stephane ; Freimoser-Grundschober, Anne ; Seeber, Stefan ; Teichgräber, Volker ; Ahmed, Rafi ; Klein, Christian ; Umaña, Pablo
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2022-10, Vol.610 (7930), p.161-172
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ArticlesPeer ReviewedFull Text
The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring
Author / Creator:Choi, Gloria B. ; Yim, Yeong S. ; Wong, Helen ; Kim, Sangdoo ; Kim, Hyunju ; Kim, Sangwon V. ; Hoeffer, Charles A. ; Littman, Dan R. ; Huh, Jun R.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2016-02, Vol.351 (6276), p.933-939
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ArticlesPeer ReviewedFull Text
Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell–driven tumor immunity
Author / Creator:Ferrari de Andrade, Lucas ; Tay, Rong En ; Pan, Deng ; Luoma, Adrienne M. ; Ito, Yoshinaga ; Badrinath, Soumya ; Tsoucas, Daphne ; Franz, Bettina ; May, Kenneth F. ; Harvey, Christopher J. ; Kobold, Sebastian ; Pyrdol, Jason W. ; Yoon, Charles ; Yuan, Guo-Cheng ; Hodi, F. Stephen ; Dranoff, Glenn ; Wucherpfennig, Kai W.
Publisher:United States: The American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2018-03, Vol.359 (6383), p.1537-1542
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ArticlesPeer ReviewedFull Text
Antibodies and venom peptides: new modalities for ion channels
Author / Creator:Wulff, Heike ; Christophersen, Palle ; Colussi, Paul ; Chandy, K. George ; Yarov-Yarovoy, Vladimir
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Drug discovery, 2019-05, Vol.18 (5), p.339-357
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Anti-CD47 antibody–mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response
Author / Creator:Tseng, Diane ; Volkmer, Jens-Peter ; Willingham, Stephen B. ; Contreras-Trujillo, Humberto ; Fathman, John W. ; Fernhoff, Nathaniel B. ; Seita, Jun ; Inlay, Matthew A. ; Weiskopf, Kipp ; Miyanishi, Masanori ; Weissman, Irving L.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-07, Vol.110 (27), p.11103-11108
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A reappraisal of CTLA-4 checkpoint blockade in cancer immunotherapy
Author / Creator:Du, Xuexiang ; Tang, Fei ; Liu, Mingyue ; Su, Juanjuan ; Zhang, Yan ; Wu, Wei ; Devenport, Martin ; Lazarski, Christopher A ; Zhang, Peng ; Wang, Xu ; Ye, Peiying ; Wang, Changyu ; Hwang, Eugene ; Zhu, Tinghui ; Xu, Ting ; Zheng, Pan ; Liu, Yang
Publisher:London: Nature Publishing Group UK
Journal title:Cell research, 2018-04, Vol.28 (4), p.416-432
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Structural basis for blocking PD-1-mediated immune suppression by therapeutic antibody pembrolizumab
Author / Creator:Na, Zhenkun ; Yeo, Siok Ping ; Bharath, Sakshibeedu R ; Bowler, Matthew W ; Balıkçı, Esra ; Wang, Cheng-I ; Song, Haiwei
Publisher:London: Nature Publishing Group UK
Journal title:Cell research, 2017-01, Vol.27 (1), p.147-150
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ArticlesPeer ReviewedFull Text
Activin Type II Receptor Blockade for Treatment of Muscle Depletion in Chronic Obstructive Pulmonary Disease. A Randomized Trial
Author / Creator:Polkey, Michael I. ; Praestgaard, Jens ; Berwick, Amy ; Franssen, Frits M. E. ; Singh, Dave ; Steiner, Michael C. ; Casaburi, Richard ; Tillmann, Hanns-Christian ; Lach-Trifilieff, Estelle ; Roubenoff, Ronenn ; Rooks, Daniel S.
Publisher:United States: American Thoracic Society
Journal title:American journal of respiratory and critical care medicine, 2019-02, Vol.199 (3), p.313-320
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ArticlesPeer ReviewedFull Text
Annexin A5 as an immune checkpoint inhibitor and tumor-homing molecule for cancer treatment
Author / Creator:Kang, Tae Heung ; Park, Jung Hwa ; Yang, Andrew ; Park, Hyun Jin ; Lee, Sung Eun ; Kim, Young Seob ; Jang, Gun-Young ; Farmer, Emily ; Lam, Brandon ; Park, Yeong-Min ; Hung, Chien-Fu
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-02, Vol.11 (1), p.1137-16, Article 1137
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ArticlesPeer ReviewedFull Text
Normalized Interferon Signatures and Clinical Improvements by IFNAR1 Blocking Antibody (Anifrolumab) in Patients with Type I Interferonopathies
Author / Creator:Kretzschmar, Genia ; Páez, Laura Piñero ; Tan, Ziyang ; Wang, Jun ; Gonzalez, Laura ; Mugabo, Constantin Habimana ; Johnsson, Anette ; Chen, Yang ; Mikeš, Jaromír ; Lakshmikanth, Tadepally ; James, Anna ; Goldbach-Mansky, Raphaela ; Fischer, Marie ; Palmblad, Karin ; Alehashemi, Sara ; Horne, AnnaCarin ; Brodin, Petter
Publisher:New York: Springer US
Journal title:Journal of clinical immunology, 2025-12, Vol.45 (1), p.31-31, Article 31
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ArticlesPeer ReviewedFull Text
Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer’s disease pathogenesis
Author / Creator:Esteve, Pilar ; Rueda-Carrasco, Javier ; Inés Mateo, María ; Martin-Bermejo, María Jesús ; Draffin, Jonathan ; Pereyra, Guadalupe ; Sandonís, África ; Crespo, Inmaculada ; Moreno, Inmaculada ; Aso, Ester ; Garcia-Esparcia, Paula ; Gomez-Tortosa, Estrella ; Rábano, Alberto ; Fortea, Juan ; Alcolea, Daniel ; Lleo, Alberto ; Heneka, Michael T. ; Valpuesta, José M. ; Esteban, José A. ; Ferrer, Isidro ; Domínguez, Mercedes ; Bovolenta, Paola
Publisher:New York: Nature Publishing Group US
Journal title:Nature neuroscience, 2019-08, Vol.22 (8), p.1258-1268
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ArticlesPeer ReviewedFull Text
Desensitization: Overcoming the Immunologic Barriers to Transplantation
Author / Creator:Peng, Alice ; Vo, Ashley ; Toyoda, Mieko ; Choi, Jua ; Sethi, Supreet ; Jordan, Stanley C.
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:Journal of immunology research, 2017-01, Vol.2017 (2017), p.1-11
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ArticlesPeer ReviewedFull Text
Extended Co-Expression of Inhibitory Receptors by Human CD8 T-Cells Depending on Differentiation, Antigen-Specificity and Anatomical Localization
Author / Creator:Baitsch, Lukas ; Legat, Amandine ; Barba, Leticia ; Fuertes Marraco, Silvia A. ; Rivals, Jean-Paul ; Baumgaertner, Petra ; Christiansen-Jucht, Céline ; Bouzourene, Hanifa ; Rimoldi, Donata ; Pircher, Hanspeter ; Rufer, Nathalie ; Matter, Maurice ; Michielin, Olivier ; Speiser, Daniel E.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-02, Vol.7 (2), p.e30852-e30852
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ArticlesPeer ReviewedFull Text
Antibody blockade of Jagged1 attenuates choroidal neovascularization
Author / Creator:Gjølberg, Torleif Tollefsrud ; Wik, Jonas Aakre ; Johannessen, Hanna ; Krüger, Stig ; Bassi, Nicola ; Christopoulos, Panagiotis F. ; Bern, Malin ; Foss, Stian ; Petrovski, Goran ; Moe, Morten C. ; Haraldsen, Guttorm ; Fosse, Johanna Hol ; Skålhegg, Bjørn Steen ; Andersen, Jan Terje ; Sundlisæter, Eirik
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-05, Vol.14 (1), p.3109-19, Article 3109
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No longer going to waste
Author / Creator:Garber, Ken
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2016-05, Vol.34 (5), p.458-461
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Diagnosis and Management of Immune-Mediated Myopathies
Author / Creator:Milone, Margherita, MD, PhD
Publisher:England: Elsevier Inc
Journal title:Mayo Clinic proceedings, 2017-05, Vol.92 (5), p.826-837
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Severe demyelination but no astrocytopathy in clinically definite neuromyelitis optica with anti-myelin-oligodendrocyte glycoprotein antibody
Author / Creator:Ikeda, Kensuke ; Kiyota, Naoki ; Kuroda, Hiroshi ; Sato, Douglas Kazutoshi ; Nishiyama, Shuhei ; Takahashi, Toshiyuki ; Misu, Tatsuro ; Nakashima, Ichiro ; Fujihara, Kazuo ; Aoki, Masashi
Publisher:London, England: SAGE Publications
Journal title:Multiple sclerosis, 2015-04, Vol.21 (5), p.656-659
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Functional differences between PD-1+ and PD-1- CD4+ effector T cells in healthy donors and patients with glioblastoma multiforme
Author / Creator:Goods, Brittany A. ; Hernandez, Amanda L. ; Lowther, Daniel E. ; Lucca, Liliana E. ; Lerner, Benjamin A. ; Gunel, Murat ; Raddassi, Khadir ; Coric, Vlad ; Hafler, David A. ; Love, J. Christopher
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-09, Vol.12 (9), p.e0181538
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ArticlesPeer ReviewedFull Text
Inhibition of TGF-β with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression
Author / Creator:Biswas, Swati ; Guix, Marta ; Rinehart, Cammie ; Dugger, Teresa C. ; Chytil, Anna ; Moses, Harold L. ; Freeman, Michael L. ; Arteaga, Carlos L.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2007-05, Vol.117 (5), p.1305-1313
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ArticlesPeer ReviewedFull Text
Targeting interleukin-17 receptor B enhances gemcitabine sensitivity through downregulation of mucins in pancreatic cancer
Author / Creator:Tsai, Lung-Hung ; Hsu, Kai-Wen ; Chiang, Cheng-Ming ; Yang, Hsiu-Ju ; Liu, Yu-Huei ; Yang, Shun-Fa ; Peng, Pei-Hua ; Cheng, Wei-Chung ; Wu, Heng-Hsiung
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-10, Vol.10 (1), p.17817, Article 17817
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PD-1-cis IL-2R agonism yields better effectors from stem-like CD8+ T cells

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The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring

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Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell–driven tumor immunity

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Antibodies and venom peptides: new modalities for ion channels

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Anti-CD47 antibody–mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response

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A reappraisal of CTLA-4 checkpoint blockade in cancer immunotherapy

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Structural basis for blocking PD-1-mediated immune suppression by therapeutic antibody pembrolizumab

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Activin Type II Receptor Blockade for Treatment of Muscle Depletion in Chronic Obstructive Pulmonary Disease. A Randomized Trial

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Annexin A5 as an immune checkpoint inhibitor and tumor-homing molecule for cancer treatment

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Normalized Interferon Signatures and Clinical Improvements by IFNAR1 Blocking Antibody (Anifrolumab) in Patients with Type I Interferonopathies

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Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer’s disease pathogenesis

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Desensitization: Overcoming the Immunologic Barriers to Transplantation

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Extended Co-Expression of Inhibitory Receptors by Human CD8 T-Cells Depending on Differentiation, Antigen-Specificity and Anatomical Localization

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Antibody blockade of Jagged1 attenuates choroidal neovascularization

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No longer going to waste

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Diagnosis and Management of Immune-Mediated Myopathies

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Severe demyelination but no astrocytopathy in clinically definite neuromyelitis optica with anti-myelin-oligodendrocyte glycoprotein antibody

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Functional differences between PD-1+ and PD-1- CD4+ effector T cells in healthy donors and patients with glioblastoma multiforme

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Inhibition of TGF-β with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression

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Targeting interleukin-17 receptor B enhances gemcitabine sensitivity through downregulation of mucins in pancreatic cancer

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