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Targeting Asparagine Metabolism in Solid Tumors
Author / Creator:Hanada, Keita ; Kawada, Kenji ; Obama, Kazutaka
Publisher:Switzerland: MDPI AG
Journal title:Nutrients, 2025-01, Vol.17 (1), p.179
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NEK8 promotes the progression of gastric cancer by reprogramming asparagine metabolism
Author / Creator:Wang, Mingliang ; Yu, Kexun ; Meng, Futao ; Wang, Huizhen ; Li, Yongxiang
Publisher:England: BioMed Central
Journal title:Molecular medicine (Cambridge, Mass.), 2025-01, Vol.31 (1), p.3-17, Article 3
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Targeting Asparagine Metabolism in Well-Differentiated/Dedifferentiated Liposarcoma
Author / Creator:Klingbeil, Kyle D ; Wilde, Blake R ; Graham, Danielle S ; Lofftus, Serena ; McCaw, Tyler ; Matulionis, Nedas ; Dry, Sarah M ; Crompton, Joseph G ; Eilber, Fritz C ; Graeber, Thomas G ; Shackelford, David B ; Christofk, Heather R ; Kadera, Brian E
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2024-08, Vol.16 (17), p.3031
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Construction of a network describing asparagine metabolism in plants and its application to the identification of genes affecting asparagine metabolism in wheat under drought and nutritional stress
Author / Creator:Curtis, Tanya Y. ; Bo, Valeria ; Tucker, Allan ; Halford, Nigel G.
Publisher:England: John Wiley & Sons, Inc
Journal title:Food and energy security, 2018-02, Vol.7 (1), p.e00126-n/a
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An asparagine metabolism-based classification reveals the metabolic and immune heterogeneity of hepatocellular carcinoma
Author / Creator:Bai, Jianguo ; Tang, Ruifeng ; Zhou, Keyu ; Chang, Jialei ; Wang, Hongyue ; Zhang, Qixin ; Shi, Jiahui ; Sun, Chao
Publisher:London: BioMed Central Ltd
Journal title:BMC medical genomics, 2022-10, Vol.15 (1), p.1-222, Article 222
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ω-Amidase: an underappreciated, but important enzyme in L-glutamine and L-asparagine metabolism; relevance to sulfur and nitrogen metabolism, tumor biology and hyperammonemic diseases
Author / Creator:Cooper, Arthur J. L ; Shurubor, Yevgeniya I ; Dorai, Thambi ; Pinto, John T ; Isakova, Elena P ; Deryabina, Yulia I ; Denton, Travis T ; Krasnikov, Boris F
Publisher:Vienna: Springer Vienna
Journal title:Amino acids, 2016-01, Vol.48 (1), p.1-20
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Relationship between asparagine metabolism and protein concentration in soybean seed
Author / Creator:Pandurangan, Sudhakar ; Pajak, Agnieszka ; Molnar, Stephen J. ; Cober, Elroy R. ; Dhaubhadel, Sangeeta ; Hernández-Sebastià, Cinta ; Kaiser, Werner M. ; Nelson, Randall L. ; Huber, Steven C. ; Marsolais, Frédéric
Publisher:Oxford: Oxford University Press
Journal title:Journal of experimental botany, 2012-05, Vol.63 (8), p.3173-3184
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Genes for asparagine metabolism in Lotus japonicus: differential expression and interconnection with photorespiration
Author / Creator:García-Calderón, Margarita ; Pérez-Delgado, Carmen M ; Credali, Alfredo ; Vega, José M ; Betti, Marco ; Márquez, Antonio J
Publisher:England: BioMed Central Ltd
Journal title:BMC genomics, 2017-10, Vol.18 (1), p.781-781, Article 781
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Asparagine Metabolism in Tumors Is Linked to Poor Survival in Females with Colorectal Cancer: A Cohort Study
Author / Creator:Shen, Xinyi ; Cai, Yuping ; Lu, Lingeng ; Huang, Huang ; Yan, Hong ; Paty, Philip B ; Muca, Engjel ; Ahuja, Nita ; Zhang, Yawei ; Johnson, Caroline H ; Khan, Sajid A
Publisher:Switzerland: MDPI AG
Journal title:Metabolites, 2022-02, Vol.12 (2), p.164
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Erratum to: ω-Amidase: an underappreciated, but important enzyme in l-glutamine and l-asparagine metabolism; relevance to sulfur and nitrogen metabolism, tumor biology and hyperammonemic diseases
Author / Creator:Cooper, Arthur J. L. ; Shurubor, Yevgeniya I. ; Dorai, Thambi ; Pinto, John T. ; Isakova, Elena P. ; Deryabina, Yulia I. ; Denton, Travis T. ; Krasnikov, Boris F.
Publisher:Vienna: Springer Vienna
Journal title:Amino acids, 2015-12, Vol.47 (12), p.2671-2672
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Erratum to: [omega]-Amidase: an underappreciated, but important enzyme in l-glutamine and l-asparagine metabolism; relevance to sulfur and nitrogen metabolism, tumor biology and hyperammonemic disease...
Author / Creator:Cooper, Arthur J; L ; Shurubor, Yevgeniya I ; Dorai, Thambi ; Pinto, John T ; Isakova, Elena P ; Deryabina, Yulia I ; Denton, Travis T ; Krasnikov, Boris F
Publisher:Vienna: Springer Nature B.V
Journal title:Amino acids, 2015-12, Vol.47 (12), p.2671
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Asparagine bioavailability governs metastasis in a model of breast cancer
Author / Creator:Knott, Simon R. V. ; Wagenblast, Elvin ; Khan, Showkhin ; Kim, Sun Y. ; Soto, Mar ; Wagner, Michel ; Turgeon, Marc-Olivier ; Fish, Lisa ; Erard, Nicolas ; Gable, Annika L. ; Maceli, Ashley R. ; Dickopf, Steffen ; Papachristou, Evangelia K. ; D’Santos, Clive S. ; Carey, Lisa A. ; Wilkinson, John E. ; Harrell, J. Chuck ; Perou, Charles M. ; Goodarzi, Hani ; Poulogiannis, George ; Hannon, Gregory J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2018-02, Vol.554 (7692), p.378-381
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Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor
Author / Creator:Krall, Abigail S. ; Xu, Shili ; Graeber, Thomas G. ; Braas, Daniel ; Christofk, Heather R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-04, Vol.7 (1), p.11457-11457, Article 11457
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Distinct mitochondrial defects trigger the integrated stress response depending on the metabolic state of the cell
Author / Creator:Mick, Eran ; Titov, Denis V ; Skinner, Owen S ; Sharma, Rohit ; Jourdain, Alexis A ; Mootha, Vamsi K
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2020-05, Vol.9
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The landscape of cancer cell line metabolism
Author / Creator:Li, Haoxin ; Ning, Shaoyang ; Ghandi, Mahmoud ; Kryukov, Gregory V. ; Gopal, Shuba ; Deik, Amy ; Souza, Amanda ; Pierce, Kerry ; Keskula, Paula ; Hernandez, Desiree ; Ann, Julie ; Shkoza, Dojna ; Apfel, Verena ; Zou, Yilong ; Vazquez, Francisca ; Barretina, Jordi ; Pagliarini, Raymond A. ; Galli, Giorgio G. ; Root, David E. ; Hahn, William C. ; Tsherniak, Aviad ; Giannakis, Marios ; Schreiber, Stuart L. ; Clish, Clary B. ; Garraway, Levi A. ; Sellers, William R.
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2019-05, Vol.25 (5), p.850-860
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Asparagine endopeptidase cleaves α-synuclein and mediates pathologic activities in Parkinson's disease
Author / Creator:Zhang, Zhentao ; Kang, Seong Su ; Liu, Xia ; Ahn, Eun Hee ; Zhang, Zhaohui ; He, Li ; Iuvone, P Michael ; Duong, Duc M ; Seyfried, Nicholas T ; Benskey, Matthew J ; Manfredsson, Fredric P ; Jin, Lingjing ; Sun, Yi E ; Wang, Jian-Zhi ; Ye, Keqiang
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2017-08, Vol.24 (8), p.632-642
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Molecular control of δ-opioid receptor signalling
Author / Creator:Fenalti, Gustavo ; Giguere, Patrick M. ; Katritch, Vsevolod ; Huang, Xi-Ping ; Thompson, Aaron A. ; Cherezov, Vadim ; Roth, Bryan L. ; Stevens, Raymond C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2014-02, Vol.506 (7487), p.191-196
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Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly
Author / Creator:Gui, Xinrui ; Luo, Feng ; Li, Yichen ; Zhou, Heng ; Qin, Zhenheng ; Liu, Zhenying ; Gu, Jinge ; Xie, Muyun ; Zhao, Kun ; Dai, Bin ; Shin, Woo Shik ; He, Jianhua ; He, Lin ; Jiang, Lin ; Zhao, Minglei ; Sun, Bo ; Li, Xueming ; Liu, Cong ; Li, Dan
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-05, Vol.10 (1), p.2006-2006, Article 2006
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Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease
Author / Creator:Zhang, Zhentao ; Song, Mingke ; Liu, Xia ; Kang, Seong Su ; Kwon, Il-Sun ; Duong, Duc M ; Seyfried, Nicholas T ; Hu, William T ; Liu, Zhixue ; Wang, Jian-Zhi ; Cheng, Liming ; Sun, Yi E ; Yu, Shan Ping ; Levey, Allan I ; Ye, Keqiang
Publisher:London: Nature Publishing Group UK
Journal title:Nature medicine, 2014-11, Vol.20 (11), p.1254-1262
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Streamlining the chemoenzymatic synthesis of complex N-glycans by a stop and go strategy
Author / Creator:Liu, Lin ; Prudden, Anthony R. ; Capicciotti, Chantelle J. ; Bosman, Gerlof P. ; Yang, Jeong-Yeh ; Chapla, Digantkumar G. ; Moremen, Kelley W. ; Boons, Geert-Jan
Publisher:London: Nature Publishing Group UK
Journal title:Nature chemistry, 2019-02, Vol.11 (2), p.161-169
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Targeting Asparagine Metabolism in Solid Tumors

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NEK8 promotes the progression of gastric cancer by reprogramming asparagine metabolism

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Targeting Asparagine Metabolism in Well-Differentiated/Dedifferentiated Liposarcoma

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Construction of a network describing asparagine metabolism in plants and its application to the identification of genes affecting asparagine metabolism in wheat under drought and nutritional stress

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An asparagine metabolism-based classification reveals the metabolic and immune heterogeneity of hepatocellular carcinoma

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ω-Amidase: an underappreciated, but important enzyme in L-glutamine and L-asparagine metabolism; relevance to sulfur and nitrogen metabolism, tumor biology and hyperammonemic diseases

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Relationship between asparagine metabolism and protein concentration in soybean seed

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Genes for asparagine metabolism in Lotus japonicus: differential expression and interconnection with photorespiration

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Asparagine Metabolism in Tumors Is Linked to Poor Survival in Females with Colorectal Cancer: A Cohort Study

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Erratum to: ω-Amidase: an underappreciated, but important enzyme in l-glutamine and l-asparagine metabolism; relevance to sulfur and nitrogen metabolism, tumor biology and hyperammonemic diseases

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Erratum to: [omega]-Amidase: an underappreciated, but important enzyme in l-glutamine and l-asparagine metabolism; relevance to sulfur and nitrogen metabolism, tumor biology and hyperammonemic disease...

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Asparagine bioavailability governs metastasis in a model of breast cancer

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Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor

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Distinct mitochondrial defects trigger the integrated stress response depending on the metabolic state of the cell

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The landscape of cancer cell line metabolism

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Asparagine endopeptidase cleaves α-synuclein and mediates pathologic activities in Parkinson's disease

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Molecular control of δ-opioid receptor signalling

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Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly

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Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease

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Streamlining the chemoenzymatic synthesis of complex N-glycans by a stop and go strategy

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