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ArticlesPeer ReviewedFull Text
Biased versus Partial Agonism in the Search for Safer Opioid Analgesics
Author / Creator:Azevedo Neto, Joaquim ; Costanzini, Anna ; De Giorgio, Roberto ; Lambert, David G ; Ruzza, Chiara ; Calò, Girolamo
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2020-08, Vol.25 (17), p.3870
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The Insect Type 1 Tyramine Receptors: From Structure to Behavior
Author / Creator:Finetti, Luca ; Roeder, Thomas ; Calò, Girolamo ; Bernacchia, Giovanni
Publisher:Switzerland: MDPI AG
Journal title:Insects (Basel, Switzerland), 2021-04, Vol.12 (4), p.315
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Effects of Stress Exposure to Pain Perception in Pre-Clinical Studies: Focus on the Nociceptin/Orphanin FQ-NOP Receptor System
Author / Creator:Pola, Pietro ; Frezza, Alessia ; Gavioli, Elaine C ; Calò, Girolamo ; Ruzza, Chiara
Publisher:Switzerland: MDPI AG
Journal title:Brain sciences, 2024-09, Vol.14 (9), p.936
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Functional Selectivity Does Not Predict Antinociceptive/Locomotor Impairing Potencies of NOP Receptor Agonists
Author / Creator:Azevedo Neto, Joaquim ; Ruzza, Chiara ; Sturaro, Chiara ; Malfacini, Davide ; Pacifico, Salvatore ; Zaveri, Nurulain T ; Calò, Girolamo
Publisher:Switzerland: Frontiers Research Foundation
Journal title:Frontiers in neuroscience, 2021-03, Vol.15, p.657153-657153
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Characterisation of the Novel Mixed Mu-NOP Peptide Ligand Dermorphin-N/OFQ (DeNo)
Author / Creator:Bird, Mark F ; Cerlesi, Maria Camilla ; Brown, Mark ; Malfacini, Davide ; Vezzi, Vanessa ; Molinari, Paola ; Micheli, Laura ; Di Cesare Mannelli, Lorenzo ; Ghelardini, Carla ; Guerrini, Remo ; Calò, Girolamo ; Lambert, David G
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-06, Vol.11 (6), p.e0156897-e0156897
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Synthesis, Biological Activity and Molecular Docking of Chimeric Peptides Targeting Opioid and NOP Receptors
Author / Creator:Wtorek, Karol ; Ghidini, Alessia ; Gentilucci, Luca ; Adamska-Bartłomiejczyk, Anna ; Piekielna-Ciesielska, Justyna ; Ruzza, Chiara ; Sturaro, Chiara ; Calò, Girolamo ; Pieretti, Stefano ; Kluczyk, Alicja ; McDonald, John ; Lambert, David G ; Janecka, Anna
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2022-10, Vol.23 (20), p.12700
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Genetic Deletion of the Nociceptin/Orphanin FQ Receptor in the Rat Confers Resilience to the Development of Drug Addiction
Author / Creator:Kallupi, Marsida ; Scuppa, Giulia ; de Guglielmo, Giordano ; Calò, Girolamo ; Weiss, Friedbert ; Statnick, Michael A ; Rorick-Kehn, Linda M ; Ciccocioppo, Roberto
Publisher:England: Nature Publishing Group
Journal title:Neuropsychopharmacology (New York, N.Y.), 2017-02, Vol.42 (3), p.695-706
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In Vitro and In Vivo Pharmaco-Toxicological Characterization of 1-Cyclohexyl-x-methoxybenzene Derivatives in Mice: Comparison with Tramadol and PCP
Author / Creator:Bilel, Sabrine ; Tirri, Micaela ; Arfè, Raffaella ; Sturaro, Chiara ; Fantinati, Anna ; Cristofori, Virginia ; Bernardi, Tatiana ; Boccuto, Federica ; Cavallo, Marco ; Cavalli, Alessandro ; De-Giorgio, Fabio ; Calò, Girolamo ; Marti, Matteo
Publisher:Basel: MDPI AG
Journal title:International journal of molecular sciences, 2021-07, Vol.22 (14), p.7659
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Hyaluronic acid induces activation of the κ-opioid receptor
Author / Creator:Zavan, Barbara ; Ferroni, Letizia ; Giorgi, Carlotta ; Calò, Girolamo ; Brun, Paola ; Cortivo, Roberta ; Abatangelo, Giovanni ; Pinton, Paolo
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013, Vol.8 (1), p.e55510
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Update of the Scientific Opinion on opium alkaloids in poppy seeds
Author / Creator:Knutsen, Helle Katrine ; Alexander, Jan ; Barregård, Lars ; Bignami, Margherita ; Brüschweiler, Beat ; Ceccatelli, Sandra ; Cottrill, Bruce ; Dinovi, Michael ; Edler, Lutz ; Grasl‐Kraupp, Bettina ; Hogstrand, Christer ; Hoogenboom, Laurentius (Ron) ; Nebbia, Carlo Stefano ; Oswald, Isabelle P ; Petersen, Annette ; Rose, Martin ; Roudot, Alain‐Claude ; Schwerdtle, Tanja ; Vollmer, Günter ; Wallace, Heather ; Benford, Diane ; Calò, Girolamo ; Dahan, Albert ; Dusemund, Birgit ; Mulder, Patrick ; Németh‐Zámboriné, Éva ; Arcella, Davide ; Baert, Katleen ; Cascio, Claudia ; Levorato, Sara ; Schutte, Marijke ; Vleminckx, Christiane
Publisher:United States: John Wiley & Sons, Inc
Journal title:EFSA journal, 2018-05, Vol.16 (5), p.e05243-n/a
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Synthesis and Structure-Activity Relationships of (-)- cis - N -Normetazocine-Based LP1 Derivatives
Author / Creator:Pasquinucci, Lorella ; Parenti, Carmela ; Amata, Emanuele ; Georgoussi, Zafiroula ; Pallaki, Paschalina ; Camarda, Valeria ; Calò, Girolamo ; Arena, Emanuela ; Montenegro, Lucia ; Turnaturi, Rita
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceuticals (Basel, Switzerland), 2018-05, Vol.11 (2), p.40
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Structure- and conformation-activity studies of nociceptin/orphanin FQ receptor dimeric ligands
Author / Creator:Pacifico, Salvatore ; Carotenuto, Alfonso ; Brancaccio, Diego ; Novellino, Ettore ; Marzola, Erika ; Ferrari, Federica ; Cerlesi, Maria Camilla ; Trapella, Claudio ; Preti, Delia ; Salvadori, Severo ; Calò, Girolamo ; Guerrini, Remo
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-04, Vol.7 (1), p.45817-45817, Article 45817
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NOP receptor pharmacological profile - A dynamic mass redistribution study
Author / Creator:Malfacini, Davide ; Simon, Katharina ; Trapella, Claudio ; Guerrini, Remo ; Zaveri, Nurulain T ; Kostenis, Evi ; Calo', Girolamo
Publisher:United States: Public Library of Science
Journal title:PloS one, 2018-08, Vol.13 (8), p.e0203021-e0203021
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NOP agonists prevent the antidepressant-like effects of nortriptyline and fluoxetine but not R-ketamine
Author / Creator:Holanda, Victor A. D. ; Santos, Wilton B. ; Asth, Laila ; Guerrini, Remo ; Calo’, Girolamo ; Ruzza, Chiara ; Gavioli, Elaine C.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Psychopharmacology, 2018-11, Vol.235 (11), p.3093-3102
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ArticlesPeer ReviewedFull Text
Synthesis and Pharmacological Evaluation of Hybrids Targeting Opioid and Neurokinin Receptors
Author / Creator:Wtorek, Karol ; Adamska-Bartłomiejczyk, Anna ; Piekielna-Ciesielska, Justyna ; Ferrari, Federica ; Ruzza, Chiara ; Kluczyk, Alicja ; Piasecka-Zelga, Joanna ; Calo', Girolamo ; Janecka, Anna
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2019-12, Vol.24 (24), p.4460
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Antidepressant activity of nociceptin/orphanin FQ receptor antagonists in the mouse learned helplessness
Author / Creator:Holanda, Victor A. D. ; Medeiros, Iris U. ; Asth, Laila ; Guerrini, Remo ; Calo’, Girolamo ; Gavioli, Elaine C.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Psychopharmacology, 2016-07, Vol.233 (13), p.2525-2532
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In vitro sepsis induces Nociceptin/Orphanin FQ receptor (NOP) expression in primary human vascular endothelial but not smooth muscle cells
Author / Creator:Mark F. Bird ; Barbara Gallacher-Horley ; John McDonald ; David G. McVey ; Fatin Al-Janabi ; Remo Guerrini ; Girolamo Calo ; Shu Ye ; Jonathan P. Thompson ; David G. Lambert
Publisher:Public Library of Science (PLoS)
Journal title:PloS one, 2022-09, Vol.17 (9)
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ArticlesPeer ReviewedFull Text
In vitro sepsis induces Nociceptin/Orphanin FQ receptor (NOP) expression in primary human vascular endothelial but not smooth muscle cells
Author / Creator:Bird, Mark F ; Gallacher-Horley, Barbara ; McDonald, John ; McVey, David G ; Al-Janabi, Fatin ; Guerrini, Remo ; Calo, Girolamo ; Ye, Shu ; Thompson, Jonathan P ; Lambert, David G
Publisher:United States: Public Library of Science
Journal title:PloS one, 2022-09, Vol.17 (9), p.e0274080-e0274080
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Blockade of NOP receptor modulates anxiety-related behaviors in mice exposed to inescapable stress
Author / Creator:Silva, Aldemara I. ; Holanda, Victor A.D. ; Azevedo Neto, Joaquim G. ; Silva Junior, Edilson D. ; Soares-Rachetti, Vanessa P. ; Calo, Girolamo ; Ruzza, Chiara ; Gavioli, Elaine C.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Psychopharmacology, 2020-06, Vol.237 (6), p.1633-1642
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Evaluation of [Cys(ATTO 488)8]Dermorphin-NH2 as a novel tool for the study of μ-opioid peptide receptors
Author / Creator:Giakomidi, Despina ; Bird, Mark F ; McDonald, John ; Marzola, Erika ; Guerrini, Remo ; Chanoch, Serena ; Sabu, Nidhuna ; Horley, Barbara ; Calo, Girolamo ; Lambert, David G
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-01, Vol.16 (4), p.e0250011-e0250011
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Showing 1 to 20 of 67 results

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Biased versus Partial Agonism in the Search for Safer Opioid Analgesics

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The Insect Type 1 Tyramine Receptors: From Structure to Behavior

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Effects of Stress Exposure to Pain Perception in Pre-Clinical Studies: Focus on the Nociceptin/Orphanin FQ-NOP Receptor System

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Functional Selectivity Does Not Predict Antinociceptive/Locomotor Impairing Potencies of NOP Receptor Agonists

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Characterisation of the Novel Mixed Mu-NOP Peptide Ligand Dermorphin-N/OFQ (DeNo)

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Synthesis, Biological Activity and Molecular Docking of Chimeric Peptides Targeting Opioid and NOP Receptors

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Genetic Deletion of the Nociceptin/Orphanin FQ Receptor in the Rat Confers Resilience to the Development of Drug Addiction

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In Vitro and In Vivo Pharmaco-Toxicological Characterization of 1-Cyclohexyl-x-methoxybenzene Derivatives in Mice: Comparison with Tramadol and PCP

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Hyaluronic acid induces activation of the κ-opioid receptor

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Update of the Scientific Opinion on opium alkaloids in poppy seeds

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Synthesis and Structure-Activity Relationships of (-)- cis - N -Normetazocine-Based LP1 Derivatives

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Structure- and conformation-activity studies of nociceptin/orphanin FQ receptor dimeric ligands

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NOP receptor pharmacological profile - A dynamic mass redistribution study

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NOP agonists prevent the antidepressant-like effects of nortriptyline and fluoxetine but not R-ketamine

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Synthesis and Pharmacological Evaluation of Hybrids Targeting Opioid and Neurokinin Receptors

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Antidepressant activity of nociceptin/orphanin FQ receptor antagonists in the mouse learned helplessness

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In vitro sepsis induces Nociceptin/Orphanin FQ receptor (NOP) expression in primary human vascular endothelial but not smooth muscle cells

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In vitro sepsis induces Nociceptin/Orphanin FQ receptor (NOP) expression in primary human vascular endothelial but not smooth muscle cells

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Blockade of NOP receptor modulates anxiety-related behaviors in mice exposed to inescapable stress

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Evaluation of [Cys(ATTO 488)8]Dermorphin-NH2 as a novel tool for the study of μ-opioid peptide receptors

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