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40 results for Autophagy-Related+Proteins+-+chemistry

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Select record 21
ArticlesPeer ReviewedFull Text
Structure of the C9orf72 ARF GAP complex that is haploinsufficient in ALS and FTD
Author / Creator:Su, Ming-Yuan ; Fromm, Simon A. ; Zoncu, Roberto ; Hurley, James H.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-09, Vol.585 (7824), p.251-255
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Structural basis for autophagy inhibition by the human Rubicon–Rab7 complex
Author / Creator:Bhargava, Hersh K. ; Tabata, Keisuke ; Byck, Jordan M. ; Hamasaki, Maho ; Farrell, Daniel P. ; Anishchenko, Ivan ; DiMaio, Frank ; Im, Young Jun ; Yoshimori, Tamotsu ; Hurley, James H.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-07, Vol.117 (29), p.17003-17010
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An N-terminal conserved region in human Atg3 couples membrane curvature sensitivity to conjugase activity during autophagy
Author / Creator:Ye, Yansheng ; Tyndall, Erin R. ; Bui, Van ; Tang, Zhenyuan ; Shen, Yan ; Jiang, Xuejun ; Flanagan, John M. ; Wang, Hong-Gang ; Tian, Fang
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-01, Vol.12 (1), p.374-374, Article 374
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Structural basis for membrane recruitment of ATG16L1 by WIPI2 in autophagy
Author / Creator:Strong, Lisa M ; Chang, Chunmei ; Riley, Julia F ; Boecker, C Alexander ; Flower, Thomas G ; Buffalo, Cosmo Z ; Ren, Xuefeng ; Stavoe, Andrea Kh ; Holzbaur, Erika Lf ; Hurley, James H
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2021-09, Vol.10
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The autophagy adaptor NDP52 and the FIP200 coiled-coil allosterically activate ULK1 complex membrane recruitment
Author / Creator:Shi, Xiaoshan ; Chang, Chunmei ; Yokom, Adam L ; Jensen, Liv E ; Hurley, James H
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2020-08, Vol.9
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ULK1 and ULK2 are less redundant than previously thought: computational analysis uncovers distinct regulation and functions of these autophagy induction proteins
Author / Creator:Demeter, Amanda ; Romero-Mulero, Mari Carmen ; Csabai, Luca ; Ölbei, Márton ; Sudhakar, Padhmanand ; Haerty, Wilfried ; Korcsmáros, Tamás
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-07, Vol.10 (1), p.10940, Article 10940
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Shared and divergent phase separation and aggregation properties of brain-expressed ubiquilins
Author / Creator:Gerson, Julia E. ; Linton, Hunter ; Xing, Jiazheng ; Sutter, Alexandra B. ; Kakos, Fayth S. ; Ryou, Jaimie ; Liggans, Nyjerus ; Sharkey, Lisa M. ; Safren, Nathaniel ; Paulson, Henry L. ; Ivanova, Magdalena I.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-01, Vol.11 (1), p.287-13, Article 287
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Receptor-like role for PQLC2 amino acid transporter in the lysosomal sensing of cationic amino acids
Author / Creator:Talaia, Gabriel ; Amick, Joseph ; Ferguson, Shawn M.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2021-02, Vol.118 (8), p.1-8
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A semisynthetic Atg3 reveals that acetylation promotes Atg3 membrane binding and Atg8 lipidation
Author / Creator:Li, Yi-Tong ; Yi, Cong ; Chen, Chen-Chen ; Lan, Huan ; Pan, Man ; Zhang, Shao-Jin ; Huang, Yi-Chao ; Guan, Chao-Jian ; Li, Yi-Ming ; Yu, Li ; Liu, Lei
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-03, Vol.8 (1), p.14846-14846, Article 14846
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Evolution from covalent conjugation to non-covalent interaction in the ubiquitin-like ATG12 system
Author / Creator:Pang, Yu ; Yamamoto, Hayashi ; Sakamoto, Hirokazu ; Oku, Masahide ; Mutungi, Joe Kimanthi ; Sahani, Mayurbhai Himatbhai ; Kurikawa, Yoshitaka ; Kita, Kiyoshi ; Noda, Nobuo N. ; Sakai, Yasuyoshi ; Jia, Honglin ; Mizushima, Noboru
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2019-04, Vol.26 (4), p.289-296
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Atg11 tethers Atg9 vesicles to initiate selective autophagy
Author / Creator:Matscheko, Nena ; Mayrhofer, Peter ; Rao, Yijian ; Beier, Viola ; Wollert, Thomas
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2019-07, Vol.17 (7), p.e3000377-e3000377
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The crystal structure of Atg18 reveals a new binding site for Atg2 in Saccharomyces cerevisiae
Author / Creator:Lei, Yuqing ; Tang, Dan ; Liao, Ga ; Xu, Liangting ; Liu, Shiyan ; Chen, Qianqian ; Li, Chunxia ; Duan, Jinsong ; Wang, Kunjie ; Wang, Jiawei ; Sun, Bo ; Li, Zhonghan ; Dai, Lunzhi ; Cheng, Wei ; Qi, Shiqian ; Lu, Kefeng
Publisher:Cham: Springer International Publishing
Journal title:Cellular and molecular life sciences : CMLS, 2021-03, Vol.78 (5), p.2131-2143
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ArticlesPeer ReviewedFull Text
A new quinoline-based chemical probe inhibits the autophagy-related cysteine protease ATG4B
Author / Creator:Bosc, D. ; Vezenkov, L. ; Bortnik, S. ; An, J. ; Xu, J. ; Choutka, C. ; Hannigan, A. M. ; Kovacic, S. ; Loo, S. ; Clark, P. G. K. ; Chen, G. ; Guay-Ross, R. N. ; Yang, K. ; Dragowska, W. H. ; Zhang, F. ; Go, N. E. ; Leung, A. ; Honson, N. S. ; Pfeifer, T. A. ; Gleave, M. ; Bally, M. ; Jones, S. J. ; Gorski, S. M. ; Young, R. N.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-08, Vol.8 (1), p.11653-17, Article 11653
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ArticlesPeer ReviewedFull Text
The T300A Crohn’s disease risk polymorphism impairs function of the WD40 domain of ATG16L1
Author / Creator:Boada-Romero, Emilio ; Serramito-Gómez, Inmaculada ; Sacristán, María P. ; Boone, David L. ; Xavier, Ramnik J. ; Pimentel-Muiños, Felipe X.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-06, Vol.7 (1), p.11821-11821, Article 11821
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Crystal structure of the Rab33B/Atg16L1 effector complex
Author / Creator:Metje-Sprink, Janina ; Groffmann, Johannes ; Neumann, Piotr ; Barg-Kues, Brigitte ; Ficner, Ralf ; Kühnel, Karin ; Schalk, Amanda M. ; Binotti, Beyenech
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-07, Vol.10 (1), p.12956-12956, Article 12956
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Structure and function of yeast Atg20, a sorting nexin that facilitates autophagy induction
Author / Creator:Popelka, Hana ; Damasio, Alejandro ; Hinshaw, Jenny E. ; Klionsky, Daniel J. ; Ragusa, Michael J.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-11, Vol.114 (47), p.E10112-E10121
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Structure based biophysical characterization of the PROPPIN Atg18 shows Atg18 oligomerization upon membrane binding
Author / Creator:Scacioc, Andreea ; Schmidt, Carla ; Hofmann, Tommy ; Urlaub, Henning ; Kühnel, Karin ; Pérez-Lara, Ángel
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-10, Vol.7 (1), p.14008-15, Article 14008
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A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation
Author / Creator:Breglio, Kimberly F ; Amato, Roberto ; Eastman, Richard ; Lim, Pharath ; Sa, Juliana M ; Guha, Rajarshi ; Ganesan, Sundar ; Dorward, David W ; Klumpp-Thomas, Carleen ; McKnight, Crystal ; Fairhurst, Rick M ; Roberts, David ; Thomas, Craig ; Simon, Anna Katharina
Publisher:England: BioMed Central Ltd
Journal title:Malaria journal, 2018-10, Vol.17 (1), p.391-391, Article 391
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Scaffolding the cup-shaped double membrane in autophagy
Author / Creator:Bahrami, Amir Houshang ; Lin, Mary G ; Ren, Xuefeng ; Hurley, James H ; Hummer, Gerhard
Publisher:United States: Public Library of Science
Journal title:PLoS computational biology, 2017-10, Vol.13 (10), p.e1005817-e1005817
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Mutation-Structure-Function Relationship Based Integrated Strategy Reveals the Potential Impact of Deleterious Missense Mutations in Autophagy Related Proteins on Hepatocellular Carcinoma (HCC): A Com...
Author / Creator:Awan, Faryal Mehwish ; Obaid, Ayesha ; Ikram, Aqsa ; Janjua, Hussnain Ahmed
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2017-01, Vol.18 (1), p.139-139
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Structure of the C9orf72 ARF GAP complex that is haploinsufficient in ALS and FTD

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Structural basis for autophagy inhibition by the human Rubicon–Rab7 complex

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An N-terminal conserved region in human Atg3 couples membrane curvature sensitivity to conjugase activity during autophagy

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Structural basis for membrane recruitment of ATG16L1 by WIPI2 in autophagy

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The autophagy adaptor NDP52 and the FIP200 coiled-coil allosterically activate ULK1 complex membrane recruitment

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ULK1 and ULK2 are less redundant than previously thought: computational analysis uncovers distinct regulation and functions of these autophagy induction proteins

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Shared and divergent phase separation and aggregation properties of brain-expressed ubiquilins

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Receptor-like role for PQLC2 amino acid transporter in the lysosomal sensing of cationic amino acids

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A semisynthetic Atg3 reveals that acetylation promotes Atg3 membrane binding and Atg8 lipidation

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Evolution from covalent conjugation to non-covalent interaction in the ubiquitin-like ATG12 system

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Atg11 tethers Atg9 vesicles to initiate selective autophagy

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The crystal structure of Atg18 reveals a new binding site for Atg2 in Saccharomyces cerevisiae

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A new quinoline-based chemical probe inhibits the autophagy-related cysteine protease ATG4B

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The T300A Crohn’s disease risk polymorphism impairs function of the WD40 domain of ATG16L1

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Crystal structure of the Rab33B/Atg16L1 effector complex

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Structure and function of yeast Atg20, a sorting nexin that facilitates autophagy induction

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Structure based biophysical characterization of the PROPPIN Atg18 shows Atg18 oligomerization upon membrane binding

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A single nucleotide polymorphism in the Plasmodium falciparum atg18 gene associates with artemisinin resistance and confers enhanced parasite survival under nutrient deprivation

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Scaffolding the cup-shaped double membrane in autophagy

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Mutation-Structure-Function Relationship Based Integrated Strategy Reveals the Potential Impact of Deleterious Missense Mutations in Autophagy Related Proteins on Hepatocellular Carcinoma (HCC): A Com...

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