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Select record 21
ArticlesPeer ReviewedFull Text
Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden
Author / Creator:O'Leary, 3rd, John C ; Li, Qingyou ; Marinec, Paul ; Blair, Laura J ; Congdon, Erin E ; Johnson, Amelia G ; Jinwal, Umesh K ; Koren, 3rd, John ; Jones, Jeffrey R ; Kraft, Clara ; Peters, Melinda ; Abisambra, Jose F ; Duff, Karen E ; Weeber, Edwin J ; Gestwicki, Jason E ; Dickey, Chad A
Publisher:England: BioMed Central Ltd
Journal title:Molecular neurodegeneration, 2010-11, Vol.5 (1), p.45-45, Article 45
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ArticlesPeer ReviewedFull Text
Tau-targeting antibody therapies: too late, wrong epitope or wrong target?
Author / Creator:Jabbari, Edwin ; Duff, Karen E.
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2021-08, Vol.27 (8), p.1341-1342
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ArticlesPeer ReviewedFull Text
Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling
Author / Creator:Myeku, Natura ; Clelland, Catherine L ; Emrani, Sheina ; Kukushkin, Nikolay V ; Yu, Wai Haung ; Goldberg, Alfred L ; Duff, Karen E
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2016-01, Vol.22 (1), p.46-53
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ArticlesPeer ReviewedFull Text
A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology
Author / Creator:Fu, Hongjun ; Possenti, Andrea ; Freer, Rosie ; Nakano, Yoshikazu ; Hernandez Villegas, Nancy C. ; Tang, Maoping ; Cauhy, Paula V. M. ; Lassus, Benjamin A. ; Chen, Shuo ; Fowler, Stephanie L. ; Figueroa, Helen Y. ; Huey, Edward D. ; Johnson, Gail V. W. ; Vendruscolo, Michele ; Duff, Karen E.
Publisher:New York: Nature Publishing Group US
Journal title:Nature neuroscience, 2019-01, Vol.22 (1), p.47-56
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ArticlesPeer ReviewedFull Text
Unilateral Focused Ultrasound-Induced Blood-Brain Barrier Opening Reduces Phosphorylated Tau from The rTg4510 Mouse Model
Author / Creator:Karakatsani, Maria Eleni ; Kugelman, Tara ; Ji, Robin ; Murillo, Maria ; Wang, Shutao ; Niimi, Yusuke ; Small, Scott A ; Duff, Karen E ; Konofagou, Elisa E
Publisher:Australia: Ivyspring International Publisher Pty Ltd
Journal title:Theranostics, 2019-01, Vol.9 (18), p.5396-5411
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ArticlesPeer ReviewedFull Text
Progressive Pathological Changes in Neurochemical Profile of the Hippocampus and Early Changes in the Olfactory Bulbs of Tau Transgenic Mice (rTg4510)
Author / Creator:Kim, Jieun ; Choi, In-Young ; Duff, Karen E. ; Lee, Phil
Publisher:New York: Springer US
Journal title:Neurochemical research, 2017-06, Vol.42 (6), p.1649-1660
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APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice
Author / Creator:Area-Gomez, Estela ; Larrea, Delfina ; Pera, Marta ; Agrawal, Rishi R. ; Guilfoyle, David N. ; Pirhaji, Leila ; Shannon, Kathleen ; Arain, Hirra A. ; Ashok, Archana ; Chen, Qiuying ; Dillman, Allissa A. ; Figueroa, Helen Y. ; Cookson, Mark R. ; Gross, Steven S. ; Fraenkel, Ernest ; Duff, Karen E. ; Nuriel, Tal
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-03, Vol.10 (1), p.4277-4277, Article 4277
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Wolframin is a novel regulator of tau pathology and neurodegeneration
Author / Creator:Chen, Shuo ; Acosta, Diana ; Li, Liangping ; Liang, Jiawen ; Chang, Yuzhou ; Wang, Cankun ; Fitzgerald, Julie ; Morrison, Cody ; Goulbourne, Chris N. ; Nakano, Yoshi ; Villegas, Nancy C. Hernandez ; Venkataraman, Lalitha ; Brown, Cris ; Serrano, Geidy E. ; Bell, Erica ; Wemlinger, Trina ; Wu, Min ; Kokiko-Cochran, Olga N. ; Popovich, Phillip ; Flowers, Xena E. ; Honig, Lawrence S. ; Vonsattel, Jean Paul ; Scharre, Douglas W. ; Beach, Thomas G. ; Ma, Qin ; Kuret, Jeff ; Kõks, Sulev ; Urano, Fumihiko ; Duff, Karen E. ; Fu, Hongjun
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Acta neuropathologica, 2022-05, Vol.143 (5), p.547-569
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Select record 29
ArticlesPeer ReviewedFull Text
Focused ultrasound mitigates pathology and improves spatial memory in Alzheimer's mice and patients
Author / Creator:Karakatsani, Maria Eleni ; Ji, Robin ; Murillo, Maria F ; Kugelman, Tara ; Kwon, Nancy ; Lao, Yeh-Hsing ; Liu, Keyu ; Pouliopoulos, Antonios N ; Honig, Lawrence S ; Duff, Karen E ; Konofagou, Elisa E
Publisher:Australia: Ivyspring International Publisher
Journal title:Theranostics, 2023-01, Vol.13 (12), p.4102-4120
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Select record 30
ArticlesPeer ReviewedFull Text
Modulation of ABCA1 by an LXR agonist reduces β-amyloid levels and improves outcome after traumatic brain injury
Author / Creator:Loane, David J ; Washington, Patricia M ; Vardanian, Lilit ; Pocivavsek, Ana ; Hoe, Hyang-Sook ; Duff, Karen E ; Cernak, Ibolja ; Rebeck, G William ; Faden, Alan I ; Burns, Mark P
Publisher:United States: Mary Ann Liebert, Inc
Journal title:Journal of neurotrauma, 2011-02, Vol.28 (2), p.225-236
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Select record 31
ArticlesPeer ReviewedFull Text
Increased Dopaminergic Neuron Sensitivity to 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) in Transgenic Mice Expressing Mutant A53T α-Synuclein
Author / Creator:Yu, Wai Haung ; Matsuoka, Yasuji ; Sziráki, István ; Hashim, Audrey ; LaFrancois, John ; Sershen, Henry ; Duff, Karen E.
Publisher:Boston: Springer US
Journal title:Neurochemical research, 2008-05, Vol.33 (5), p.902-911
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Select record 32
ArticlesPeer ReviewedFull Text
APOE4 Alters Tau Propagation in Regions Associated with Early Alzheimer’s Disease in a Humanized Mouse Model of Tau Spread
Author / Creator:Arain, Hirra A ; Idiarte, Juan F ; Lama, Tsering D ; Figueroa, Helen Y ; Guo, Jia ; Duff, Karen E ; Nuriel, Tal
Publisher:Hoboken: John Wiley and Sons Inc
Journal title:Alzheimer's & dementia, 2024-12, Vol.20 (S1), p.n/a
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Select record 33
ArticlesPeer ReviewedFull Text
Basic Science and Pathogenesis
Author / Creator:Arain, Hirra A ; Idiarte, Juan F ; Lama, Tsering D ; Figueroa, Helen Y ; Guo, Jia ; Duff, Karen E ; Nuriel, Tal
Publisher:United States
Journal title:Alzheimer's & dementia, 2024-12, Vol.20 Suppl 1, p.e089837
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Select record 34
ArticlesPeer ReviewedFull Text
Chemogenetic attenuation of neuronal activity in the entorhinal cortex reduces A[beta] and tau pathology in the hippocampus
Author / Creator:Rodriguez, Gustavo A ; Barrett, Geoffrey M ; Duff, Karen E ; Hussaini, S. Abid ; Gasque, Gabriel
Publisher:Public Library of Science
Journal title:PLoS biology, 2020-08, Vol.18 (8)
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Select record 35
ArticlesFull Text
GPCR-mediated clearance of tau in post-synaptic compartments attenuates tau pathology in vivo
Author / Creator:Myeku, Natura ; Schaler, Ari W ; Runyan, Avery M ; Fowler, Stephanie L ; Figueroa, Helen Y ; Shioda, Seiji ; Ismael Santa Maria ; Duff, Karen E
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-01
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Select record 36
ArticlesFull Text
APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice
Author / Creator:Nuriel, Tal ; Larrea, Delfina ; Guilfoyle, David N ; Pirhaji, Leila ; Shannon, Kathleen ; Arain, Hirra ; Ashok, Archana ; Pera, Marta ; Chen, Qiuying ; Dillman, Allissa A ; Figueroa, Helen Y ; Cookson, Mark R ; Gross, Steven S ; Fraenkel, Ernest ; Duff, Karen E ; Area-Gomez, Estela
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2018-12
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Select record 37
ArticlesPeer ReviewedFull Text
Journal of Neurotrauma
Author / Creator:Loane, David J ; Washington, Patricia M ; Vardanian, Lilit ; Pocivavsek, Ana ; Hoe, Hyang-Sook ; Duff, Karen E ; Cernak, Ibolja ; Rebeck, G William ; Faden, Alan I ; Burns, Mark P
Publisher:New York: Mary Ann Liebert, Inc
Journal title:Journal of neurotrauma, 2011-02, Vol.28 (2), p.225
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Select record 38
ArticlesPeer ReviewedFull Text
Increased Dopaminergic Neuron Sensitivity to 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) in Transgenic Mice Expressing Mutant A53T [alpha]-Synuclein
Author / Creator:Yu, Wai Haung ; Matsuoka, Yasuji ; Sziráki, István ; Hashim, Audrey ; LaFrancois, John ; Sershen, Henry ; Duff, Karen E
Publisher:New York: Springer Nature B.V
Journal title:Neurochemical research, 2008-05, Vol.33 (5), p.902-911
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Select record 39
ReportsFull Text
Chemogenetic attenuation of neuronal activity in the entorhinal cortex reduces A[beta] and tau pathology in the hippocampus
Author / Creator:Rodriguez, Gustavo A ; Barrett, Geoffrey M ; Duff, Karen E ; Hussaini, S. Abid ; Gasque, Gabriel
Publisher:Public Library of Science
Journal title:PLoS Biology, 2020, Vol.18 (8)
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Select record 40
ArticlesFull Text
Attenuation of entorhinal cortex hyperactivity reduces Aβ and tau pathology
Author / Creator:Rodriguez, Gustavo A ; Barrett, Geoffrey M ; Duff, Karen E ; Hussaini, Abid
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2019-03
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Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden

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Tau-targeting antibody therapies: too late, wrong epitope or wrong target?

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Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling

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A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology

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Unilateral Focused Ultrasound-Induced Blood-Brain Barrier Opening Reduces Phosphorylated Tau from The rTg4510 Mouse Model

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Progressive Pathological Changes in Neurochemical Profile of the Hippocampus and Early Changes in the Olfactory Bulbs of Tau Transgenic Mice (rTg4510)

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APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice

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Wolframin is a novel regulator of tau pathology and neurodegeneration

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Focused ultrasound mitigates pathology and improves spatial memory in Alzheimer's mice and patients

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Modulation of ABCA1 by an LXR agonist reduces β-amyloid levels and improves outcome after traumatic brain injury

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Increased Dopaminergic Neuron Sensitivity to 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) in Transgenic Mice Expressing Mutant A53T α-Synuclein

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APOE4 Alters Tau Propagation in Regions Associated with Early Alzheimer’s Disease in a Humanized Mouse Model of Tau Spread

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Basic Science and Pathogenesis

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Chemogenetic attenuation of neuronal activity in the entorhinal cortex reduces A[beta] and tau pathology in the hippocampus

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GPCR-mediated clearance of tau in post-synaptic compartments attenuates tau pathology in vivo

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APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice

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Journal of Neurotrauma

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Increased Dopaminergic Neuron Sensitivity to 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) in Transgenic Mice Expressing Mutant A53T [alpha]-Synuclein

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Chemogenetic attenuation of neuronal activity in the entorhinal cortex reduces A[beta] and tau pathology in the hippocampus

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Attenuation of entorhinal cortex hyperactivity reduces Aβ and tau pathology

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