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358 results for Glycosylation+-+drug+effects

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ArticlesPeer ReviewedFull Text
The essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesis
Author / Creator:Zhang, Xiao ; Qiao, Yongxia ; Wu, Qi ; Chen, Yan ; Zou, Shaowu ; Liu, Xiangfan ; Zhu, Guoqing ; Zhao, Yinghui ; Chen, Yuxin ; Yu, Yongchun ; Pan, Qiuhui ; Wang, Jiayi ; Sun, Fenyong
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-05, Vol.8 (1), p.15280-15, Article 15280
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Potential of Sorghum Seeds in Alleviating Hyperglycemia, Oxidative Stress, and Glycation Damage
Author / Creator:Ben El Mahdi, Nora ; Lemée, Laurent ; Remaury, Quentin Blancart ; Eloy, Lilian ; Nhiri, Naima ; Lakhssassi, Naoufal ; Cacciola, Francesco ; Nhiri, Mohamed
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2024-08, Vol.29 (15), p.3445
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Interleukin-22-mediated host glycosylation prevents Clostridioides difficile infection by modulating the metabolic activity of the gut microbiota
Author / Creator:Nagao-Kitamoto, Hiroko ; Leslie, Jhansi L. ; Kitamoto, Sho ; Jin, Chunsheng ; Thomsson, Kristina A. ; Gillilland, Merritt G. ; Kuffa, Peter ; Goto, Yoshiyuki ; Jenq, Robert R. ; Ishii, Chiharu ; Hirayama, Akiyoshi ; Seekatz, Anna M. ; Martens, Eric C. ; Eaton, Kathryn A. ; Kao, John Y. ; Fukuda, Shinji ; Higgins, Peter D. R. ; Karlsson, Niclas G. ; Young, Vincent B. ; Kamada, Nobuhiko
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2020-04, Vol.26 (4), p.608-617
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Inhibition of SARS-CoV-2 viral entry upon blocking N- and O-glycan elaboration
Author / Creator:Yang, Qi ; Hughes, Thomas A ; Kelkar, Anju ; Yu, Xinheng ; Cheng, Kai ; Park, Sheldon ; Huang, Wei-Chiao ; Lovell, Jonathan F ; Neelamegham, Sriram
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2020-10, Vol.9
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Reversible histone glycation is associated with disease-related changes in chromatin architecture
Author / Creator:Zheng, Qingfei ; Omans, Nathaniel D. ; Leicher, Rachel ; Osunsade, Adewola ; Agustinus, Albert S. ; Finkin-Groner, Efrat ; D’Ambrosio, Hannah ; Liu, Bo ; Chandarlapaty, Sarat ; Liu, Shixin ; David, Yael
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-03, Vol.10 (1), p.1289-1289, Article 1289
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Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation
Author / Creator:Erickson, Jeffrey R. ; Pereira, Laetitia ; Wang, Lianguo ; Han, Guanghui ; Ferguson, Amanda ; Dao, Khanha ; Copeland, Ronald J. ; Despa, Florin ; Hart, Gerald W. ; Ripplinger, Crystal M. ; Bers, Donald M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2013-10, Vol.502 (7471), p.372-376
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Tunicamycin specifically aggravates ER stress and overcomes chemoresistance in multidrug-resistant gastric cancer cells by inhibiting N-glycosylation
Author / Creator:Wu, Jian ; Chen, Sheng ; Liu, Hao ; Zhang, Zhe ; Ni, Zhen ; Chen, Jie ; Yang, Zhiping ; Nie, Yongzhan ; Fan, Daiming
Publisher:England: BioMed Central Ltd
Journal title:Journal of experimental & clinical cancer research, 2018-11, Vol.37 (1), p.272-272, Article 272
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Catalytic activation of glycosyl phosphates for stereoselective coupling reactions
Author / Creator:Levi, Samuel M. ; Li, Qiuhan ; Rötheli, Andreas R. ; Jacobsen, Eric N.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-01, Vol.116 (1), p.35-39
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AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation
Author / Creator:Gélinas, Roselle ; Mailleux, Florence ; Dontaine, Justine ; Bultot, Laurent ; Demeulder, Bénédicte ; Ginion, Audrey ; Daskalopoulos, Evangelos P. ; Esfahani, Hrag ; Dubois-Deruy, Emilie ; Lauzier, Benjamin ; Gauthier, Chantal ; Olson, Aaron K. ; Bouchard, Bertrand ; Des Rosiers, Christine ; Viollet, Benoit ; Sakamoto, Kei ; Balligand, Jean-Luc ; Vanoverschelde, Jean-Louis ; Beauloye, Christophe ; Horman, Sandrine ; Bertrand, Luc
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-01, Vol.9 (1), p.374-17, Article 374
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Controlled tetra-Fc sialylation of IVIg results in a drug candidate with consistent enhanced anti-inflammatory activity
Author / Creator:Washburn, Nathaniel ; Schwab, Inessa ; Ortiz, Daniel ; Bhatnagar, Naveen ; Lansing, Jonathan C. ; Medeiros, Amy ; Tyler, Steven ; Mekala, Divya ; Cochran, Edward ; Sarvaiya, Hetal ; Garofalo, Kevin ; Meccariello, Robin ; Meador, James W. ; Rutitzky, Laura ; Schultes, Birgit C. ; Ling, Leona ; Avery, William ; Nimmerjahn, Falk ; Manning, Anthony M. ; Kaundinya, Ganesh V. ; Bosques, Carlos J.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (11), p.E1297-E1306
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ArticlesPeer ReviewedFull Text
MUCILAGE-RELATED10 Produces Galactoglucomannan That Maintains Pectin and Cellulose Architecture in Arabidopsis Seed Mucilage
Author / Creator:Voiniciuc, Cătălin ; Schmidt, Maximilian Heinrich-Wilhelm ; Berger, Adeline ; Yang, Bo ; Ebert, Berit ; Scheller, Henrik V. ; North, Helen M. ; Usadel, Björn ; Günl, Markus
Publisher:United States: American Society of Plant Biologists
Journal title:Plant physiology (Bethesda), 2015-09, Vol.169 (1), p.403-420
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Defective glycosylation of coagulation factor XII underlies hereditary angioedema type III
Author / Creator:Björkqvist, Jenny ; de Maat, Steven ; Lewandrowski, Urs ; Di Gennaro, Antonio ; Oschatz, Chris ; Schönig, Kai ; Nöthen, Markus M. ; Drouet, Christian ; Braley, Hal ; Nolte, Marc W. ; Sickmann, Albert ; Panousis, Con ; Maas, Coen ; Renné, Thomas
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2015-08, Vol.125 (8), p.3132-3146
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A systematic study of modulation of ADAM-mediated ectodomain shedding by site-specific O-glycosylation
Author / Creator:Goth, Christoffer K. ; Halim, Adnan ; Khetarpal, Sumeet A. ; Rader, Daniel J. ; Clausen, Henrik ; Schjoldager, Katrine T.-B. G.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2015-11, Vol.112 (47), p.14623-14628
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Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16
Author / Creator:Pancera, Marie ; Shahzad-ul-Hussan, Syed ; Doria-Rose, Nicole A ; McLellan, Jason S ; Bailer, Robert T ; Dai, Kaifan ; Loesgen, Sandra ; Louder, Mark K ; Staupe, Ryan P ; Yang, Yongping ; Zhang, Baoshan ; Parks, Robert ; Eudailey, Joshua ; Lloyd, Krissey E ; Blinn, Julie ; Alam, S Munir ; Haynes, Barton F ; Amin, Mohammed N ; Wang, Lai-Xi ; Burton, Dennis R ; Koff, Wayne C ; Nabel, Gary J ; Mascola, John R ; Bewley, Carole A ; Kwong, Peter D
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2013-07, Vol.20 (7), p.804-813
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Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120
Author / Creator:Kong, Leopold ; Lee, Jeong Hyun ; Doores, Katie J ; Murin, Charles D ; Julien, Jean-Philippe ; McBride, Ryan ; Liu, Yan ; Marozsan, Andre ; Cupo, Albert ; Klasse, Per-Johan ; Hoffenberg, Simon ; Caulfield, Michael ; King, C Richter ; Hua, Yuanzi ; Le, Khoa M ; Khayat, Reza ; Deller, Marc C ; Clayton, Thomas ; Tien, Henry ; Feizi, Ten ; Sanders, Rogier W ; Paulson, James C ; Moore, John P ; Stanfield, Robyn L ; Burton, Dennis R ; Ward, Andrew B ; Wilson, Ian A
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2013-07, Vol.20 (7), p.796-803
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Small-molecule control of antibody N-glycosylation in engineered mammalian cells
Author / Creator:Chang, Michelle M. ; Gaidukov, Leonid ; Jung, Giyoung ; Tseng, Wen Allen ; Scarcelli, John J. ; Cornell, Richard ; Marshall, Jeffrey K. ; Lyles, Jonathan L. ; Sakorafas, Paul ; Chu, An-Hsiang Adam ; Cote, Kaffa ; Tzvetkova, Boriana ; Dolatshahi, Sepideh ; Sumit, Madhuresh ; Mulukutla, Bhanu Chandra ; Lauffenburger, Douglas A. ; Figueroa, Bruno ; Summers, Nevin M. ; Lu, Timothy K. ; Weiss, Ron
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2019-07, Vol.15 (7), p.730-736
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Ribitol restores functionally glycosylated α-dystroglycan and improves muscle function in dystrophic FKRP-mutant mice
Author / Creator:Cataldi, Marcela P. ; Lu, Peijuan ; Blaeser, Anthony ; Lu, Qi Long
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-08, Vol.9 (1), p.3448-12, Article 3448
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Structures of human O-GlcNAcase and its complexes reveal a new substrate recognition mode
Author / Creator:Li, Baobin ; Li, Hao ; Lu, Lei ; Jiang, Jiaoyang
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2017-04, Vol.24 (4), p.362-369
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High-throughput decoding of antitrypanosomal drug efficacy and resistance
Author / Creator:Alsford, Sam ; Eckert, Sabine ; Baker, Nicola ; Glover, Lucy ; Sanchez-Flores, Alejandro ; Leung, Ka Fai ; Turner, Daniel J. ; Field, Mark C. ; Berriman, Matthew ; Horn, David
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2012-02, Vol.482 (7384), p.232-236
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Galactose Supplementation in Patients With TMEM165-CDG Rescues the Glycosylation Defects
Author / Creator:Morelle, Willy ; Potelle, Sven ; Witters, Peter ; Wong, Sunnie ; Climer, Leslie ; Lupashin, Vladimir ; Matthijs, Gert ; Gadomski, Therese ; Jaeken, Jaak ; Cassiman, David ; Morava, Eva ; Foulquier, François
Publisher:Washington, DC: Endocrine Society
Journal title:The journal of clinical endocrinology and metabolism, 2017-04, Vol.102 (4), p.1375-1386
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The essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesis

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Potential of Sorghum Seeds in Alleviating Hyperglycemia, Oxidative Stress, and Glycation Damage

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Interleukin-22-mediated host glycosylation prevents Clostridioides difficile infection by modulating the metabolic activity of the gut microbiota

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Inhibition of SARS-CoV-2 viral entry upon blocking N- and O-glycan elaboration

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Reversible histone glycation is associated with disease-related changes in chromatin architecture

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Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation

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Tunicamycin specifically aggravates ER stress and overcomes chemoresistance in multidrug-resistant gastric cancer cells by inhibiting N-glycosylation

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Catalytic activation of glycosyl phosphates for stereoselective coupling reactions

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AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation

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Controlled tetra-Fc sialylation of IVIg results in a drug candidate with consistent enhanced anti-inflammatory activity

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MUCILAGE-RELATED10 Produces Galactoglucomannan That Maintains Pectin and Cellulose Architecture in Arabidopsis Seed Mucilage

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Defective glycosylation of coagulation factor XII underlies hereditary angioedema type III

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A systematic study of modulation of ADAM-mediated ectodomain shedding by site-specific O-glycosylation

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Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16

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Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120

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Small-molecule control of antibody N-glycosylation in engineered mammalian cells

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Ribitol restores functionally glycosylated α-dystroglycan and improves muscle function in dystrophic FKRP-mutant mice

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Structures of human O-GlcNAcase and its complexes reveal a new substrate recognition mode

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High-throughput decoding of antitrypanosomal drug efficacy and resistance

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Galactose Supplementation in Patients With TMEM165-CDG Rescues the Glycosylation Defects

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