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258 results for Poly(ADP-ribose)+Polymerases+-+deficiency

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Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
Author / Creator:Bryant, Helen E. ; Schultz, Niklas ; Thomas, Huw D. ; Parker, Kayan M. ; Flower, Dan ; Lopez, Elena ; Kyle, Suzanne ; Meuth, Mark ; Curtin, Nicola J. ; Helleday, Thomas
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2005-04, Vol.434 (7035), p.913-917
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Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression
Author / Creator:Boehler, Christian ; Gauthier, Laurent R ; Mortusewicz, Oliver ; Biard, Denis S ; Saliou, Jean-Michel ; Bresson, Anne ; Sanglier-Cianferani, Sarah ; Smith, Susan ; Schreiber, Valérie ; Boussin, François ; Dantzer, Françoise
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2011-02, Vol.108 (7), p.2783-2788
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Coordinated signals from the DNA repair enzymes PARP-1 and PARP-2 promotes B-cell development and function
Author / Creator:Galindo-Campos, Miguel A. ; Bedora-Faure, Marie ; Farrés, Jordi ; Lescale, Chloé ; Moreno-Lama, Lucia ; Martínez, Carlos ; Martín-Caballero, Juan ; Ampurdanés, Coral ; Aparicio, Pedro ; Dantzer, Françoise ; Cerutti, Andrea ; Deriano, Ludovic ; Yélamos, José
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2019-12, Vol.26 (12), p.2667-2681
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Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
Author / Creator:Farmer, Hannah ; McCabe, Nuala ; Lord, Christopher J. ; Tutt, Andrew N. J. ; Johnson, Damian A. ; Richardson, Tobias B. ; Santarosa, Manuela ; Dillon, Krystyna J. ; Hickson, Ian ; Knights, Charlotte ; Martin, Niall M. B. ; Jackson, Stephen P. ; Smith, Graeme C. M. ; Ashworth, Alan
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2005-04, Vol.434 (7035), p.917-921
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Differential regulation of breast cancer bone metastasis by PARP1 and PARP2
Author / Creator:Zuo, Hao ; Yang, Dengbao ; Yang, Qiwen ; Tang, Haidong ; Fu, Yang-Xin ; Wan, Yihong
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-03, Vol.11 (1), p.1578-10, Article 1578
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Poly(ADP-ribose) polymerase 1 activation is required for cisplatin nephrotoxicity
Author / Creator:Kim, Jinu ; Long, Kelly E. ; Tang, Kang ; Padanilam, Babu J.
Publisher:Basingstoke: Elsevier Inc
Journal title:Kidney international, 2012-07, Vol.82 (2), p.193-203
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Role of Poly(ADP-Ribose) Polymerase Activation in Diabetic Neuropathy
Author / Creator:OBROSOVA, Irina G ; FEI LI ; ABATAN, Omorodola I ; FORSELL, Mark A ; KOMJATI, Katalin ; PACHER, Pal ; SZABO, Csaba ; STEVENS, Martin J
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2004-03, Vol.53 (3), p.711-720
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PARP-1 controls immunosuppressive function of regulatory T cells by destabilizing Foxp3
Author / Creator:Zhang, Pin ; Maruyama, Takashi ; Konkel, Joanne E ; Abbatiello, Brittany ; Zamarron, Brian ; Wang, Zhao-qi ; Chen, Wanjun
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013, Vol.8 (8), p.e71590
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PARP inhibitors for cancer therapy
Author / Creator:Curtin, Nicola J.
Publisher:Cambridge, UK: Cambridge University Press
Journal title:Expert reviews in molecular medicine, 2005-03, Vol.7 (4), p.1-20
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Poly(ADP-Ribose) Polymerase-2 Contributes to the Fidelity of Male Meiosis I and Spermiogenesis
Author / Creator:Dantzer, Françoise ; Mark, Manuel ; Quenet, Delphine ; Scherthan, Harry ; Huber, Aline ; Liebe, Bodo ; Monaco, Lucia ; Chicheportiche, Alexandra ; Sassone-Corsi, Paolo ; de Murcia, Gilbert ; Ménissier-de Murcia, Josiane
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2006-10, Vol.103 (40), p.14854-14859
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PARP inhibition restores extrinsic apoptotic sensitivity in glioblastoma
Author / Creator:Karpel-Massler, Georg ; Pareja, Fresia ; Aimé, Pascaline ; Shu, Chang ; Chau, Lily ; Westhoff, Mike-Andrew ; Halatsch, Marc-Eric ; Crary, John F ; Canoll, Peter ; Siegelin, Markus D
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-12, Vol.9 (12), p.e114583
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Vasoactivity of rucaparib, a PARP-1 inhibitor, is a complex process that involves myosin light chain kinase, P2 receptors, and PARP itself
Author / Creator:McCrudden, Cian M ; O'Rourke, Martin G ; Cherry, Kim E ; Yuen, Hiu-Fung ; O'Rourke, Declan ; Babur, Muhammad ; Telfer, Brian A ; Thomas, Huw D ; Keane, Patrick ; Nambirajan, Thiagarajan ; Hagan, Chris ; O'Sullivan, Joe M ; Shaw, Chris ; Williams, Kaye J ; Curtin, Nicola J ; Hirst, David G ; Robson, Tracy
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-02, Vol.10 (2), p.e0118187-e0118187
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PARP10 suppresses tumor metastasis through regulation of Aurora A activity
Author / Creator:Zhao, Yahui ; Hu, Xiaoding ; Wei, Li ; Song, Dan ; Wang, Juanjuan ; You, Lifang ; Saiyin, Hexige ; Li, Zhaojie ; Yu, Wenbo ; Yu, Long ; Ding, Jin ; Wu, Jiaxue
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2018-05, Vol.37 (22), p.2921-2935
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Poly(ADP-Ribose) Polymerase-Deficient Mice Are Protected from Streptozotocin-Induced Diabetes
Author / Creator:Pieper, Andrew A. ; Brat, Daniel J. ; Krug, David K. ; Watkins, Crystal C. ; Gupta, Alok ; Blackshaw, Seth ; Verma, Ajay ; Wang, Zhao-Qi ; Snyder, Solomon H.
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1999-03, Vol.96 (6), p.3059-3064
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PARP-2 deficiency affects the survival of CD4+CD8+ double-positive thymocytes
Author / Creator:Yélamos, José ; Monreal, Yolanda ; Saenz, Luis ; Aguado, Enrique ; Schreiber, Valérie ; Mota, Rubén ; Fuente, Teodomiro ; Minguela, Alfredo ; Parrilla, Pascual ; de Murcia, Gilbert ; Almarza, Elena ; Aparicio, Pedro ; Ménissier-de Murcia, Josiane
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:The EMBO journal, 2006-09, Vol.25 (18), p.4350-4360
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Interaction between ATM and PARP-1 in response to DNA damage and sensitization of ATM deficient cells through PARP inhibition
Author / Creator:Aguilar-Quesada, Rocío ; Muñoz-Gámez, José Antonio ; Martín-Oliva, David ; Peralta, Andreína ; Valenzuela, Maria Teresa ; Matínez-Romero, Rubén ; Quiles-Pérez, Rosa ; Menissier-de Murcia, Josiane ; de Murcia, Gilbert ; Ruiz de Almodóvar, Mariano ; Oliver, F Javier
Publisher:England: BioMed Central Ltd
Journal title:BMC molecular biology, 2007-04, Vol.8 (1), p.29-29, Article 29
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Loss of poly(ADP-ribose) polymerase-2 leads to rapid development of spontaneous T-cell lymphomas in p53-deficient mice
Author / Creator:Nicolás, L ; Martínez, C ; Baró, C ; Rodríguez, M ; Baroja-Mazo, A ; Sole, F ; Flores, J M ; Ampurdanés, C ; Dantzer, F ; Martin-Caballero, J ; Aparicio, P ; Yelamos, J
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2010-05, Vol.29 (19), p.2877-2883
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Poly(ADP-Ribose) Polymerase Gene Disruption Conferred Mice Resistant to Streptozotocin-Induced Diabetes
Author / Creator:Masutani, Mitsuko ; Suzuki, Hiroshi ; Kamada, Nobuo ; Watanabe, Miho ; Ueda, Otoya ; Nozaki, Tadashige ; Jishage, Kou-ichi ; Watanabe, Takeshi ; Sugimoto, Tetsuro ; Nakagama, Hitoshi ; Ochiya, Takahiro ; Sugimura, Takashi
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1999-03, Vol.96 (5), p.2301-2304
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Protection against Hemorrhagic Shock in Mice Genetically Deficient in Poly(ADP-Ribose)Polymerase
Author / Creator:Liaudet, L ; Soriano, F G ; Szabó, E ; Virág, L ; Mabley, J G ; Salzman, A L ; Szabo, C
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2000-08, Vol.97 (18), p.10203-10208
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Poly (ADP-ribose) transferase/polymerase-1-deficient mice resistant to age-dependent decrease in β-cell proliferation
Author / Creator:Gong, Lei ; Liu, Fu-Qiang ; Wang, Ying ; Hou, Xin-Guo ; Zhang, Wei ; Qin, Wei-Dong ; Zhang, Yun ; Chen, Li ; Zhang, Ming-Xiang
Publisher:England: BioMed Central
Journal title:Molecular medicine (Cambridge, Mass.), 2012-07, Vol.18 (5), p.816-824
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Showing 1 to 20 of 258 results

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Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

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Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression

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Coordinated signals from the DNA repair enzymes PARP-1 and PARP-2 promotes B-cell development and function

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Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

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Differential regulation of breast cancer bone metastasis by PARP1 and PARP2

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Poly(ADP-ribose) polymerase 1 activation is required for cisplatin nephrotoxicity

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Role of Poly(ADP-Ribose) Polymerase Activation in Diabetic Neuropathy

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PARP-1 controls immunosuppressive function of regulatory T cells by destabilizing Foxp3

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PARP inhibitors for cancer therapy

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Poly(ADP-Ribose) Polymerase-2 Contributes to the Fidelity of Male Meiosis I and Spermiogenesis

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PARP inhibition restores extrinsic apoptotic sensitivity in glioblastoma

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Vasoactivity of rucaparib, a PARP-1 inhibitor, is a complex process that involves myosin light chain kinase, P2 receptors, and PARP itself

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PARP10 suppresses tumor metastasis through regulation of Aurora A activity

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Poly(ADP-Ribose) Polymerase-Deficient Mice Are Protected from Streptozotocin-Induced Diabetes

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PARP-2 deficiency affects the survival of CD4+CD8+ double-positive thymocytes

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Interaction between ATM and PARP-1 in response to DNA damage and sensitization of ATM deficient cells through PARP inhibition

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Loss of poly(ADP-ribose) polymerase-2 leads to rapid development of spontaneous T-cell lymphomas in p53-deficient mice

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Poly(ADP-Ribose) Polymerase Gene Disruption Conferred Mice Resistant to Streptozotocin-Induced Diabetes

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Protection against Hemorrhagic Shock in Mice Genetically Deficient in Poly(ADP-Ribose)Polymerase

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Poly (ADP-ribose) transferase/polymerase-1-deficient mice resistant to age-dependent decrease in β-cell proliferation

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