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ArticlesPeer ReviewedFull Text
NAD+ metabolism governs the proinflammatory senescence-associated secretome
Author / Creator:Nacarelli, Timothy ; Lau, Lena ; Fukumoto, Takeshi ; Zundell, Joseph ; Fatkhutdinov, Nail ; Wu, Shuai ; Aird, Katherine M. ; Iwasaki, Osamu ; Kossenkov, Andrew V. ; Schultz, David ; Noma, Ken-ichi ; Baur, Joseph A. ; Schug, Zachary ; Tang, Hsin-Yao ; Speicher, David W. ; David, Gregory ; Zhang, Rugang
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2019-03, Vol.21 (3), p.397-407
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Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers
Author / Creator:Bitler, Benjamin G ; Aird, Katherine M ; Garipov, Azat ; Li, Hua ; Amatangelo, Michael ; Kossenkov, Andrew V ; Schultz, David C ; Liu, Qin ; Shih, Ie-Ming ; Conejo-Garcia, Jose R ; Speicher, David W ; Zhang, Rugang
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2015-03, Vol.21 (3), p.231-238
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ARID1A-mutated ovarian cancers depend on HDAC6 activity
Author / Creator:Bitler, Benjamin G. ; Wu, Shuai ; Park, Pyoung Hwa ; Hai, Yang ; Aird, Katherine M. ; Wang, Yemin ; Zhai, Yali ; Kossenkov, Andrew V. ; Vara-Ailor, Ana ; Rauscher III, Frank J. ; Zou, Weiping ; Speicher, David W. ; Huntsman, David G. ; Conejo-Garcia, Jose R. ; Cho, Kathleen R. ; Christianson, David W. ; Zhang, Rugang
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2017-08, Vol.19 (8), p.962-973
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PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion
Author / Creator:Caino, M. Cecilia ; Jagadish C. Ghosh ; Young Chan Chae ; Valentina Vaira ; Dayana B. Rivadeneira ; Alice Faversani ; Paolo Rampini ; Andrew V. Kossenkov ; Katherine M. Aird ; Rugang Zhang ; Marie R. Webster ; Ashani T. Weeraratna ; Silvano Bosari ; Lucia R. Languino ; Dario C. Altieri
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2015-07, Vol.112 (28), p.8638-8643
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Topoisomerase 1 cleavage complex enables pattern recognition and inflammation during senescence
Author / Creator:Zhao, Bo ; Liu, Pingyu ; Fukumoto, Takeshi ; Nacarelli, Timothy ; Fatkhutdinov, Nail ; Wu, Shuai ; Lin, Jianhuang ; Aird, Katherine M. ; Tang, Hsin-Yao ; Liu, Qin ; Speicher, David W. ; Zhang, Rugang
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-02, Vol.11 (1), p.908-908, Article 908
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Context-dependent activation of SIRT3 is necessary for anchorage-independent survival and metastasis of ovarian cancer cells
Author / Creator:Kim, Yeon Soo ; Gupta Vallur, Piyushi ; Jones, Victoria M. ; Worley, Beth L. ; Shimko, Sara ; Shin, Dong-Hui ; Crawford, LaTaijah C. ; Chen, Chi-Wei ; Aird, Katherine M. ; Abraham, Thomas ; Shepherd, Trevor G. ; Warrick, Joshua I. ; Lee, Nam Y. ; Phaeton, Rebecca ; Mythreye, Karthikeyan ; Hempel, Nadine
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2020-02, Vol.39 (8), p.1619-1633
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Overexpression of oncogenic H-Ras in hTERT-immortalized and SV40-transformed human cells targets replicative and specialized DNA polymerases for depletion
Author / Creator:Tsao, Wei-chung ; Buj, Raquel ; Aird, Katherine M. ; Sidorova, Julia M. ; Eckert, Kristin A.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-05, Vol.16 (5), p.e0251188-e0251188
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CLIC1 and CLIC4 complement CA125 as a diagnostic biomarker panel for all subtypes of epithelial ovarian cancer
Author / Creator:Singha, Bipradeb ; Harper, Sandra L. ; Goldman, Aaron R. ; Bitler, Benjamin G. ; Aird, Katherine M. ; Borowsky, Mark E. ; Cadungog, Mark G. ; Liu, Qin ; Zhang, Rugang ; Jean, Stephanie ; Drapkin, Ronny ; Speicher, David W.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-10, Vol.8 (1), p.14725-14, Article 14725
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53BP1: guarding the genome with a novel liquid weapon
Author / Creator:Tangudu, Naveen Kumar ; Aird, Katherine M.
Publisher:London: Nature Publishing Group UK
Journal title:Communications biology, 2022-05, Vol.5 (1), p.435-435, Article 435
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Loss of p16: A Bouncer of the Immunological Surveillance?
Author / Creator:Leon, Kelly E. ; Tangudu, Naveen Kumar ; Aird, Katherine M. ; Buj, Raquel
Publisher:Switzerland: MDPI AG
Journal title:Life (Basel, Switzerland), 2021-04, Vol.11 (4), p.309
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ArticlesPeer ReviewedFull Text
Jumonji C Demethylases in Cellular Senescence
Author / Creator:Leon, Kelly E. ; Aird, Katherine M.
Publisher:Switzerland: MDPI AG
Journal title:Genes, 2019-01, Vol.10 (1), p.33
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D-MAINS: A Deep-Learning Model for the Label-Free Detection of Mitosis, Apoptosis, Interphase, Necrosis, and Senescence in Cancer Cells
Author / Creator:He, Sarah ; Sillah, Muhammed ; Cole, Aidan R. ; Uboveja, Apoorva ; Aird, Katherine M. ; Chen, Yu-Chih ; Gong, Yi-Nan
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2024-06, Vol.13 (12), p.1004
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sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance
Author / Creator:Kaur, Amanpreet ; Webster, Marie R. ; Marchbank, Katie ; Behera, Reeti ; Ndoye, Abibatou ; Kugel, Curtis H. ; Dang, Vanessa M. ; Appleton, Jessica ; O’Connell, Michael P. ; Cheng, Phil ; Valiga, Alexander A. ; Morissette, Rachel ; McDonnell, Nazli B. ; Ferrucci, Luigi ; Kossenkov, Andrew V. ; Meeth, Katrina ; Tang, Hsin-Yao ; Yin, Xiangfan ; Wood, William H. ; Lehrmann, Elin ; Becker, Kevin G. ; Flaherty, Keith T. ; Frederick, Dennie T. ; Wargo, Jennifer A. ; Cooper, Zachary A. ; Tetzlaff, Michael T. ; Hudgens, Courtney ; Aird, Katherine M. ; Zhang, Rugang ; Xu, Xiaowei ; Liu, Qin ; Bartlett, Edmund ; Karakousis, Giorgos ; Eroglu, Zeynep ; Lo, Roger S. ; Chan, Matthew ; Menzies, Alexander M. ; Long, Georgina V. ; Johnson, Douglas B. ; Sosman, Jeffrey ; Schilling, Bastian ; Schadendorf, Dirk ; Speicher, David W. ; Bosenberg, Marcus ; Ribas, Antoni ; Weeraratna, Ashani T.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-04, Vol.532 (7598), p.250-254
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Ovarian cancer: how can resistance to chemotherapy be tackled?
Author / Creator:Karakashev, Sergey ; Aird, Katherine M
Publisher:England: Future Medicine Ltd
Journal title:Future oncology (London, England), 2017-12, Vol.13 (30), p.2737-2739
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CASC4/GOLM2 drives high grade serous carcinoma anoikis resistance through the recycling of EGFR
Author / Creator:Bapat, Jaidev ; Yamamoto, Tomomi M. ; Woodruff, Elizabeth R. ; Qamar, Lubna ; Mikeska, Railey G. ; Aird, Katherine M. ; Watson, Zachary L. ; Brubaker, Lindsay W. ; Bitler, Benjamin G.
Publisher:New York: Nature Publishing Group US
Journal title:Cancer gene therapy, 2024-02, Vol.31 (2), p.300-310
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ErbB1/2 tyrosine kinase inhibitor mediates oxidative stress-induced apoptosis in inflammatory breast cancer cells
Author / Creator:Aird, Katherine M. ; Allensworth, Jennifer L. ; Batinic-Haberle, Ines ; Lyerly, H. Kim ; Dewhirst, Mark W. ; Devi, Gayathri R.
Publisher:Boston: Springer US
Journal title:Breast cancer research and treatment, 2012-02, Vol.132 (1), p.109-119
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GPX3 supports ovarian cancer tumor progression in vivo and promotes expression of GDF15
Author / Creator:Chang, Caroline ; Ya-Yun, Cheng ; Kamlapurkar, Shriya ; White, Sierra R ; Tang, Priscilla W ; Elhaw, Amal T ; Javed, Zaineb ; Aird, Katherine M ; Karthikeyan Mythreye ; Phaeton, Rebecca ; Hempel, Nadine
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2024-01
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Paracrine effects of the senescence-associated secretory phenotype decrease cancer cell adhesion
Author / Creator:Cole, Aidan R ; Buj, Raquel ; Amal Taher Elhaw ; Uboveja, Apoorva ; Tangudu, Naveen Kumar ; Oesterreich, Steffi ; Stallaert, Wayne ; Hempel, Nadine ; Aird, Katherine M
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2023-12
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NAD.sup.+ metabolism governs the proinflammatory senescence-associated secretome
Author / Creator:Nacarelli, Timothy ; Lau, Lena ; Fukumoto, Takeshi ; Zundell, Joseph ; Fatkhutdinov, Nail ; Wu, Shuai ; Aird, Katherine M
Publisher:Nature Publishing Group
Journal title:Nature cell biology, 2019-03, Vol.21 (3), p.397
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Suppression of p16 alleviates the senescence-associated secretory phenotype
Author / Creator:Buj, Raquel ; Leon, Kelly E ; Aird, Katherine M
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-08
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Showing 1 to 20 of 34 results

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NAD+ metabolism governs the proinflammatory senescence-associated secretome

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Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers

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ARID1A-mutated ovarian cancers depend on HDAC6 activity

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PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion

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Topoisomerase 1 cleavage complex enables pattern recognition and inflammation during senescence

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Context-dependent activation of SIRT3 is necessary for anchorage-independent survival and metastasis of ovarian cancer cells

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Overexpression of oncogenic H-Ras in hTERT-immortalized and SV40-transformed human cells targets replicative and specialized DNA polymerases for depletion

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CLIC1 and CLIC4 complement CA125 as a diagnostic biomarker panel for all subtypes of epithelial ovarian cancer

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53BP1: guarding the genome with a novel liquid weapon

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Loss of p16: A Bouncer of the Immunological Surveillance?

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Jumonji C Demethylases in Cellular Senescence

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D-MAINS: A Deep-Learning Model for the Label-Free Detection of Mitosis, Apoptosis, Interphase, Necrosis, and Senescence in Cancer Cells

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sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance

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Ovarian cancer: how can resistance to chemotherapy be tackled?

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CASC4/GOLM2 drives high grade serous carcinoma anoikis resistance through the recycling of EGFR

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ErbB1/2 tyrosine kinase inhibitor mediates oxidative stress-induced apoptosis in inflammatory breast cancer cells

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GPX3 supports ovarian cancer tumor progression in vivo and promotes expression of GDF15

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Paracrine effects of the senescence-associated secretory phenotype decrease cancer cell adhesion

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NAD.sup.+ metabolism governs the proinflammatory senescence-associated secretome

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Suppression of p16 alleviates the senescence-associated secretory phenotype

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