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CLASPs prevent irreversible multipolarity by ensuring spindle-pole resistance to traction forces during chromosome alignment
Author / Creator:Logarinho, Elsa ; Maffini, Stefano ; Barisic, Marin ; Marques, Andrea ; Toso, Alberto ; Meraldi, Patrick ; Maiato, Helder
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2012-03, Vol.14 (3), p.295-303
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Ran stimulates spindle assembly by altering microtubule dynamics and the balance of motor activities
Author / Creator:Wilde, Andrew ; Lizarraga, Sofia B. ; Zhang, Lijun ; Wiese, Christiane ; Gliksman, Neal R. ; Walczak, Claire E. ; Zheng, Yixian
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2001-03, Vol.3 (3), p.221-227
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Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition
Author / Creator:Cohen-Sharir, Yael ; McFarland, James M. ; Abdusamad, Mai ; Marquis, Carolyn ; Bernhard, Sara V. ; Kazachkova, Mariya ; Tang, Helen ; Ippolito, Marica R. ; Laue, Kathrin ; Zerbib, Johanna ; Malaby, Heidi L. H. ; Jones, Andrew ; Stautmeister, Lisa-Marie ; Bockaj, Irena ; Wardenaar, René ; Lyons, Nicholas ; Nagaraja, Ankur ; Bass, Adam J. ; Spierings, Diana C. J. ; Foijer, Floris ; Beroukhim, Rameen ; Santaguida, Stefano ; Golub, Todd R. ; Stumpff, Jason ; Storchová, Zuzana ; Ben-David, Uri
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-02, Vol.590 (7846), p.486-491
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Whole-genome doubling confers unique genetic vulnerabilities on tumour cells
Author / Creator:Quinton, Ryan J. ; DiDomizio, Amanda ; Vittoria, Marc A. ; Kotýnková, Kristýna ; Ticas, Carlos J. ; Patel, Sheena ; Koga, Yusuke ; Vakhshoorzadeh, Jasmine ; Hermance, Nicole ; Kuroda, Taruho S. ; Parulekar, Neha ; Taylor, Alison M. ; Manning, Amity L. ; Campbell, Joshua D. ; Ganem, Neil J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-02, Vol.590 (7846), p.492-497
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Mild replication stress causes chromosome mis-segregation via premature centriole disengagement
Author / Creator:Wilhelm, Therese ; Olziersky, Anna-Maria ; Harry, Daniela ; De Sousa, Filipe ; Vassal, Helène ; Eskat, Anja ; Meraldi, Patrick
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-08, Vol.10 (1), p.3585-14, Article 3585
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A choreography of centrosomal mRNAs reveals a conserved localization mechanism involving active polysome transport
Author / Creator:Safieddine, Adham ; Coleno, Emeline ; Salloum, Soha ; Imbert, Arthur ; Traboulsi, Abdel-Meneem ; Kwon, Oh Sung ; Lionneton, Frederic ; Georget, Virginie ; Robert, Marie-Cécile ; Gostan, Thierry ; Lecellier, Charles-Henri ; Chouaib, Racha ; Pichon, Xavier ; Le Hir, Hervé ; Zibara, Kazem ; Mueller, Florian ; Walter, Thomas ; Peter, Marion ; Bertrand, Edouard
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-03, Vol.12 (1), p.1352-21, Article 1352
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Mechanism for remodelling of the cell cycle checkpoint protein MAD2 by the ATPase TRIP13
Author / Creator:Alfieri, Claudio ; Chang, Leifu ; Barford, David
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2018-07, Vol.559 (7713), p.274-278
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TRIM37 controls cancer-specific vulnerability to PLK4 inhibition
Author / Creator:Meitinger, Franz ; Ohta, Midori ; Lee, Kian-Yong ; Watanabe, Sadanori ; Davis, Robert L. ; Anzola, John V. ; Kabeche, Ruth ; Jenkins, David A. ; Shiau, Andrew K. ; Desai, Arshad ; Oegema, Karen
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-09, Vol.585 (7825), p.440-446
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Plasmodium chaperonin TRiC/CCT identified as a target of the antihistamine clemastine using parallel chemoproteomic strategy
Author / Creator:Lu, Kuan-Yi ; Quan, Baiyi ; Sylvester, Kayla ; Srivastava, Tamanna ; Fitzgerald, Michael C. ; Derbyshire, Emily R.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-03, Vol.117 (11), p.5810-5817
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Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein
Author / Creator:Firestone, Ari J. ; Weinger, Joshua S. ; Maldonado, Maria ; Barlan, Kari ; Langston, Lance D. ; O’Donnell, Michael ; Gelfand, Vladimir I. ; Kapoor, Tarun M. ; Chen, James K.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2012-04, Vol.484 (7392), p.125-129
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Active forces shape the metaphase spindle through a mechanical instability
Author / Creator:Oriola, David ; Jülicher, Frank ; Brugués, Jan
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-07, Vol.117 (28), p.16154-16159
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Chromosomal instability and cancer: a complex relationship with therapeutic potential
Author / Creator:Bakhoum, Samuel F ; Compton, Duane A
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2012-04, Vol.122 (4), p.1138-1143
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KIF15 nanomechanics and kinesin inhibitors, with implications for cancer chemotherapeutics
Author / Creator:Milic, Bojan ; Chakraborty, Anirban ; Han, Kyuho ; Bassik, Michael C. ; Block, Steven M.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-05, Vol.115 (20), p.E4613-E4622
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ArticlesPeer ReviewedFull Text
Cell cycle alterations induced by urban PM2.5 in bronchial epithelial cells: characterization of the process and possible mechanisms involved
Author / Creator:Longhin, Eleonora ; Holme, Jørn A ; Gutzkow, Kristine B ; Arlt, Volker M ; Kucab, Jill E ; Camatini, Marina ; Gualtieri, Maurizio
Publisher:England: BioMed Central Ltd
Journal title:Particle and fibre toxicology, 2013-12, Vol.10 (1), p.63-63
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Structural basis of human kinesin-8 function and inhibition
Author / Creator:Locke, Julia ; Joseph, Agnel Praveen ; Peña, Alejandro ; Möckel, Martin M. ; Mayer, Thomas U. ; Topf, Maya ; Moores, Carolyn A.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-11, Vol.114 (45), p.E9539-E9548
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ArticlesPeer ReviewedFull Text
Microtubules as a target for anticancer drugs
Author / Creator:Jordan, Mary Ann ; Wilson, Leslie
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2004-04, Vol.4 (4), p.253-265
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MiR-584-5p potentiates vincristine and radiation response by inducing spindle defects and DNA damage in medulloblastoma
Author / Creator:Abdelfattah, Nourhan ; Rajamanickam, Subapriya ; Panneerdoss, Subbarayalu ; Timilsina, Santosh ; Yadav, Pooja ; Onyeagucha, Benjamin C. ; Garcia, Michael ; Vadlamudi, Ratna ; Chen, Yidong ; Brenner, Andrew ; Houghton, Peter ; Rao, Manjeet K.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-10, Vol.9 (1), p.4541-19, Article 4541
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Dynamic maintenance of asymmetric meiotic spindle position through Arp2/3-complex-driven cytoplasmic streaming in mouse oocytes
Author / Creator:Yi, Kexi ; Unruh, Jay R. ; Deng, Manqi ; Slaughter, Brian D. ; Rubinstein, Boris ; Li, Rong
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2011-10, Vol.13 (10), p.1252-1258
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Paradoxical mitotic exit induced by a small molecule inhibitor of APC/C Cdc20
Author / Creator:Richeson, Katherine V ; Bodrug, Tatyana ; Sackton, Katharine L ; Yamaguchi, Masaya ; Paulo, Joao A ; Gygi, Steven P ; Schulman, Brenda A ; Brown, Nicholas G ; King, Randall W
Publisher:United States
Journal title:Nature chemical biology, 2020-05, Vol.16 (5), p.546
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Complete microtubule–kinetochore occupancy favours the segregation of merotelic attachments
Author / Creator:Dudka, Damian ; Noatynska, Anna ; Smith, Chris A. ; Liaudet, Nicolas ; McAinsh, Andrew D. ; Meraldi, Patrick
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-05, Vol.9 (1), p.2042-16, Article 2042
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Showing 1 to 20 of 215 results

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CLASPs prevent irreversible multipolarity by ensuring spindle-pole resistance to traction forces during chromosome alignment

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Ran stimulates spindle assembly by altering microtubule dynamics and the balance of motor activities

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Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition

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Whole-genome doubling confers unique genetic vulnerabilities on tumour cells

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Mild replication stress causes chromosome mis-segregation via premature centriole disengagement

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A choreography of centrosomal mRNAs reveals a conserved localization mechanism involving active polysome transport

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Mechanism for remodelling of the cell cycle checkpoint protein MAD2 by the ATPase TRIP13

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TRIM37 controls cancer-specific vulnerability to PLK4 inhibition

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Plasmodium chaperonin TRiC/CCT identified as a target of the antihistamine clemastine using parallel chemoproteomic strategy

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Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein

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Active forces shape the metaphase spindle through a mechanical instability

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Chromosomal instability and cancer: a complex relationship with therapeutic potential

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KIF15 nanomechanics and kinesin inhibitors, with implications for cancer chemotherapeutics

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Cell cycle alterations induced by urban PM2.5 in bronchial epithelial cells: characterization of the process and possible mechanisms involved

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Structural basis of human kinesin-8 function and inhibition

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Microtubules as a target for anticancer drugs

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MiR-584-5p potentiates vincristine and radiation response by inducing spindle defects and DNA damage in medulloblastoma

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Dynamic maintenance of asymmetric meiotic spindle position through Arp2/3-complex-driven cytoplasmic streaming in mouse oocytes

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Paradoxical mitotic exit induced by a small molecule inhibitor of APC/C Cdc20

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Complete microtubule–kinetochore occupancy favours the segregation of merotelic attachments

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